Literature DB >> 17534529

Reactivity patterns of cytochrome P450 enzymes: multifunctionality of the active species, and the two states-two oxidants conundrum.

Sason Shaik1, Hajime Hirao, Devesh Kumar.   

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Year:  2007        PMID: 17534529     DOI: 10.1039/b604192m

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN: 0265-0568            Impact factor:   13.423


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  13 in total

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Review 3.  Diversity of P450 enzymes in the biosynthesis of natural products.

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7.  A single-site mutation (F429H) converts the enzyme CYP 2B4 into a heme oxygenase: a QM/MM study.

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8.  Importance of substituents in ring opening: a DFT study on a model reaction of thiazole to thioamide.

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Journal:  J Mol Model       Date:  2021-02-21       Impact factor: 1.810

9.  Specific knockdown of uPA/uPAR attenuates invasion in glioblastoma cells and xenografts by inhibition of cleavage and trafficking of Notch -1 receptor.

Authors:  Hari Raghu; Christopher S Gondi; Dzung H Dinh; Meena Gujrati; Jasti S Rao
Journal:  Mol Cancer       Date:  2011-10-17       Impact factor: 27.401

10.  Importance of H-abstraction in the final step of nitrosoalkane formation in the mechanism-based inactivation of cytochrome P450 by amine-containing drugs.

Authors:  Hajime Hirao; Nandun M Thellamurege; Pratanphorn Chuanprasit; Kai Xu
Journal:  Int J Mol Sci       Date:  2013-12-18       Impact factor: 5.923

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