Literature DB >> 22017381

Enzymatic chemistry of cyclopropane, epoxide, and aziridine biosynthesis.

Christopher J Thibodeaux1, Wei-chen Chang, Hung-wen Liu.   

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Year:  2011        PMID: 22017381      PMCID: PMC3288687          DOI: 10.1021/cr200073d

Source DB:  PubMed          Journal:  Chem Rev        ISSN: 0009-2665            Impact factor:   60.622


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  184 in total

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7.  Biosynthetic studies of aziridine formation in azicemicins.

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8.  Characterization of the azinomycin B biosynthetic gene cluster revealing a different iterative type I polyketide synthase for naphthoate biosynthesis.

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9.  The enzymology of polyether biosynthesis.

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10.  Molecular cloning, characterization, and overexpression of ERG7, the Saccharomyces cerevisiae gene encoding lanosterol synthase.

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2.  Protein engineering: Chemistry gets the assist.

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Review 3.  Nonproteinogenic amino acid building blocks for nonribosomal peptide and hybrid polyketide scaffolds.

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Review 4.  Oxidative Cyclization in Natural Product Biosynthesis.

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Review 5.  Heteroatom-Heteroatom Bond Formation in Natural Product Biosynthesis.

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6.  Epoxidation Catalyzed by the Nonheme Iron(II)- and 2-Oxoglutarate-Dependent Oxygenase, AsqJ: Mechanistic Elucidation of Oxygen Atom Transfer by a Ferryl Intermediate.

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7.  Evidence that the fosfomycin-producing epoxidase, HppE, is a non-heme-iron peroxidase.

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8.  Alternative Reactivity of Leucine 5-Hydroxylase Using an Olefin-Containing Substrate to Construct a Substituted Piperidine Ring.

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9.  Direct stereospecific synthesis of unprotected N-H and N-Me aziridines from olefins.

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10.  Evidence for radical-mediated catalysis by HppE: a study using cyclopropyl and methylenecyclopropyl substrate analogues.

Authors:  Hui Huang; Wei-chen Chang; Pei-Jing Pai; Anthony Romo; Steven O Mansoorabadi; David H Russell; Hung-wen Liu
Journal:  J Am Chem Soc       Date:  2012-09-24       Impact factor: 15.419

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