| Literature DB >> 1741756 |
H M Jespersen1, E A MacGregor, M R Sierks, B Svensson.
Abstract
Structure-prediction and hydrophobic-cluster analysis of several starch hydrolases and related enzymes indicated the organization of eleven domain types. Most enzymes possess a catalytic (beta/alpha)8-barrel and a smaller C-terminal domain as seen in crystal structures of alpha-amylase and cyclodextrin glucanotransferase. Some also have a starch-granule-binding domain. Enzymes breaking or forming endo-alpha-1,6 linkages contain domains N-terminal to the (beta/alpha)8-barrel.Entities:
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Year: 1991 PMID: 1741756 PMCID: PMC1130598 DOI: 10.1042/bj2800051
Source DB: PubMed Journal: Biochem J ISSN: 0264-6021 Impact factor: 3.857