Literature DB >> 17404468

Dose delivered from Varian's CBCT to patients receiving IMRT for prostate cancer.

Ning Wen1, Huaiqun Guan, Rabih Hammoud, Deepak Pradhan, T Nurushev, Shidong Li, Benjamin Movsas.   

Abstract

With the increased use of cone beam CT (CBCT) for daily patient setup, the accumulated dose from CBCT may be significantly higher than that from simulation CT or portal imaging. The objective of this work is to measure the dose from daily pelvic scans with fixed technical settings and collimations. CBCT scans were acquired in half-fan mode using a half bowtie and x-rays were delivered in pulsed-fluoro mode. The skin doses for seven prostate patients were measured on an IRB-approved protocol. TLD capsules were placed on the patient's skin at the central axis of three beams: AP, left lateral (Lt Lat) and right lateral (Rt Lat). To avoid the ring artefacts centred in the prostate, the treatment couch was dropped 3 cm from the patient's tattoo (central axis). The measured AP skin doses ranged 3-6 cGy for 20-33 cm separation. The larger the patient size the less the AP skin dose. Lateral doses did not change much with patient size. The Lt Lat dose was approximately 4.0 cGy, which was approximately 40% higher than the Rt Lat dose of approximately 2.6 cGy. To verify this dose asymmetry, surface doses on an IMRT QA phantom (oval shaped, 30 cm x 20 cm) were measured at the same three sites using TLD capsules with 3 cm table-drop. The dose asymmetry was due to: (1) kV source rotation which always starts from the patient's Lt Lat and ends at Lt Lat. Gantry rotation gets much slower near the end of rotation but dose rate stays constant and (2) 370 degrees scan rotation (10 degrees scan overlap on the Lt Lat side). In vivo doses were measured inside a Rando pelvic heterogeneous phantom using TLDs. The left hip (femoral head and neck) received the highest doses of approximately 10-11 cGy while the right hip received approximately 6-7 cGy. The surface and in vivo doses were also measured for phantoms at the central-axis setup. The difference was less than approximately 12% to the table-drop setup.

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Year:  2007        PMID: 17404468     DOI: 10.1088/0031-9155/52/8/015

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  27 in total

1.  Compressed sensing based cone-beam computed tomography reconstruction with a first-order method.

Authors:  Kihwan Choi; Jing Wang; Lei Zhu; Tae-Suk Suh; Stephen Boyd; Lei Xing
Journal:  Med Phys       Date:  2010-09       Impact factor: 4.071

2.  Monte Carlo evaluation of scatter mitigation strategies in cone-beam CT.

Authors:  Dimitrios Lazos; Jeffrey F Williamson
Journal:  Med Phys       Date:  2010-10       Impact factor: 4.071

3.  Iterative image reconstruction for CBCT using edge-preserving prior.

Authors:  Jing Wang; Tianfang Li; Lei Xing
Journal:  Med Phys       Date:  2009-01       Impact factor: 4.071

4.  Development and validation of a measurement-based source model for kilovoltage cone-beam CT Monte Carlo dosimetry simulations.

Authors:  Kyle McMillan; Michael McNitt-Gray; Dan Ruan
Journal:  Med Phys       Date:  2013-11       Impact factor: 4.071

5.  Progressive cone beam CT dose control in image-guided radiation therapy.

Authors:  Hao Yan; Xin Zhen; Laura Cerviño; Steve B Jiang; Xun Jia
Journal:  Med Phys       Date:  2013-06       Impact factor: 4.071

6.  Fast reconstruction of digital tomosynthesis using on-board images.

Authors:  Hui Yan; Devon J Godfrey; Fang-Fang Yin
Journal:  Med Phys       Date:  2008-05       Impact factor: 4.071

7.  Monte Carlo calculation of imaging doses from diagnostic multidetector CT and kilovoltage cone-beam CT as part of prostate cancer treatment plans.

Authors:  Aiping Ding; Jianwei Gu; Alexei V Trofimov; X George Xu
Journal:  Med Phys       Date:  2010-12       Impact factor: 4.071

8.  Structure-adaptive CBCT reconstruction using weighted total variation and Hessian penalties.

Authors:  Qi Shi; Nanbo Sun; Tao Sun; Jing Wang; Shan Tan
Journal:  Biomed Opt Express       Date:  2016-08-09       Impact factor: 3.732

9.  Reconstructing cone-beam CT with spatially varying qualities for adaptive radiotherapy: a proof-of-principle study.

Authors:  Wenting Lu; Hao Yan; Xuejun Gu; Zhen Tian; Ouyang Luo; Liu Yang; Linghong Zhou; Laura Cervino; Jing Wang; Steve Jiang; Xun Jia
Journal:  Phys Med Biol       Date:  2014-09-26       Impact factor: 3.609

10.  Impact of reduction of flux overlap region on kilovoltage cone-beam computed tomography image quality and patients' exposure dose.

Authors:  Daisuke Kawahara; Shuichi Ozawa; Yuji Murakami; Takeo Nakashima; Masamichi Aita; Shintaro Tsuda; Yusuke Ochi; Takuro Okumura; Hirokazu Masuda; Yoshimi Ohno; Yasushi Nagata
Journal:  Rep Pract Oncol Radiother       Date:  2016-05-16
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