Literature DB >> 17371821

In vitro activities of miltefosine and two novel antifungal biscationic salts against a panel of 77 dermatophytes.

Zhongsheng Tong1, Fred Widmer, Tania C Sorrell, Zofia Guse, Katrina A Jolliffe, Catriona Halliday, Ok Cha Lee, Fanrong Kong, Lesley C Wright, Sharon C A Chen.   

Abstract

The susceptibilities of 77 dermatophytes to miltefosine (MI), 1,12-bis(4-pentylpyridinium)dodecane (PYR), 1,12-bis(tributylammonium)dodecane (AM), itraconazole (ITC), terbinafine (TRB), and butenafine (BTF) were compared. Geometric mean MICs of TRB, BTF, ITC, MI, PYR, and AM were 0.039, 0.059, 1.718, 0.671, 6.006, and 4.771 microg/ml, respectively. MI was more active than ITC (P < 0.001).

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Year:  2007        PMID： 17371821      PMCID： PMC1891392          DOI： 10.1128/AAC.01382-06

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  29 in total

1.  Intra- and interlaboratory study of a method for testing the antifungal susceptibilities of dermatophytes.

Authors:  M A Ghannoum; V Chaturvedi; A Espinel-Ingroff; M A Pfaller; M G Rinaldi; W Lee-Yang; D W Warnock
Journal:  J Clin Microbiol       Date:  2004-07       Impact factor: 5.948

2.  In vitro susceptibility testing of dermatophytes: comparison of disk diffusion and reference broth dilution methods.

Authors:  Nuriye Karaca; A Nedret Koç
Journal:  Diagn Microbiol Infect Dis       Date:  2004-04       Impact factor: 2.803

3.  In vitro antifungal activities of inhibitors of phospholipases from the fungal pathogen Cryptococcus neoformans.

Authors:  Ranjini Ganendren; Fred Widmer; Vatsala Singhal; Christabel Wilson; Tania Sorrell; Lesley Wright
Journal:  Antimicrob Agents Chemother       Date:  2004-05       Impact factor: 5.191

4.  Prevalence of onychomycosis in patients attending a dermatology clinic in northeastern Ohio for other conditions.

Authors:  B E Elewski; M A Charif
Journal:  Arch Dermatol       Date:  1997-09

5.  Lipolytic enzymes of Trichophyton rubrum.

Authors:  S K Das; A B Banerjee
Journal:  Sabouraudia       Date:  1977-11

6.  Optimal growth conditions for the determination of the antifungal susceptibility of three species of dermatophytes with the use of a microdilution method.

Authors:  H A Norris; B E Elewski; M A Ghannoum
Journal:  J Am Acad Dermatol       Date:  1999-06       Impact factor: 11.527

7.  Extracellular enzyme activities of dermatophytes and yeast isolates on solid media.

Authors:  T M Muhsin; A H Aubaid; A H al-Duboon
Journal:  Mycoses       Date:  1997-12       Impact factor: 4.377

8.  Miltefosine (Impavido): the first oral treatment against leishmaniasis.

Authors:  H Sindermann; S L Croft; K R Engel; W Bommer; H J Eibl; C Unger; J Engel
Journal:  Med Microbiol Immunol       Date:  2003-09-26       Impact factor: 3.402

9.  Evaluation of in vitro resistance in patients with onychomycosis who fail antifungal therapy.

Authors:  Aditya K Gupta; Yatika Kohli
Journal:  Dermatology       Date:  2003       Impact factor: 5.366

10.  Hexadecylphosphocholine: determination of serum concentrations in rats.

Authors:  C Unger; E Fleer; W Damenz; P Hilgard; G Nagel; H Eibl
Journal:  J Lipid Mediat       Date:  1991 Jan-Feb
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  9 in total

1.  In Vitro Activities of Miltefosine and Antibacterial Agents from the Macrolide, Oxazolidinone, and Pleuromutilin Classes against Pythium insidiosum and Pythium aphanidermatum.

Authors:  Erico S Loreto; Juliana S M Tondolo; Daniele C Oliveira; Janio M Santurio; Sydney H Alves
Journal:  Antimicrob Agents Chemother       Date:  2018-02-23       Impact factor: 5.191

2.  Miltefosine Has a Postantifungal Effect and Induces Apoptosis in Cryptococcus Yeasts.

Authors:  Cristina de Castro Spadari; Taissa Vila; Sonia Rozental; Kelly Ishida
Journal:  Antimicrob Agents Chemother       Date:  2018-07-27       Impact factor: 5.191

3.  Limited activity of miltefosine in murine models of cryptococcal meningoencephalitis and disseminated cryptococcosis.

Authors:  Nathan P Wiederhold; Laura K Najvar; Rosie Bocanegra; William R Kirkpatrick; Tania C Sorrell; Thomas F Patterson
Journal:  Antimicrob Agents Chemother       Date:  2012-11-19       Impact factor: 5.191

4.  Fatal invasive infection with fungemia due to Microascus cirrosus after heart and lung transplantation in a patient with cystic fibrosis.

Authors:  Charline Miossec; Florent Morio; Thierry Lepoivre; Patrice Le Pape; Dea Garcia-Hermoso; Françoise Gay-Andrieu; Alain Haloun; Michele Treilhaud; François Leclair; Michel Miegeville
Journal:  J Clin Microbiol       Date:  2011-05-04       Impact factor: 5.948

5.  Synthesis and antifungal activities of miltefosine analogs.

Authors:  Ranga Rao Ravu; Ying-Lien Chen; Melissa R Jacob; Xuewen Pan; Ameeta K Agarwal; Shabana I Khan; Joseph Heitman; Alice M Clark; Xing-Cong Li
Journal:  Bioorg Med Chem Lett       Date:  2013-07-06       Impact factor: 2.823

6.  In Vitro Activity of Miltefosine against Candida albicans under Planktonic and Biofilm Growth Conditions and In Vivo Efficacy in a Murine Model of Oral Candidiasis.

Authors:  Taissa Vieira Machado Vila; Ashok K Chaturvedi; Sonia Rozental; Jose L Lopez-Ribot
Journal:  Antimicrob Agents Chemother       Date:  2015-09-28       Impact factor: 5.191

7.  Therapeutic switching: from antidermatophytic essential oils to new leishmanicidal products.

Authors:  Emeline Houël; German Gonzalez; Jean-Marie Bessière; Guillaume Odonne; Véronique Eparvier; Eric Deharo; Didier Stien
Journal:  Mem Inst Oswaldo Cruz       Date:  2015-02-13       Impact factor: 2.743

8.  In Vitro Antifungal Susceptibility Profile of Miltefosine against a Collection of Azole and Echinocandins Resistant Fusarium Strains.

Authors:  Mohsen Nosratabadi; Javad Akhtari; Leila Faeli; Iman Haghani; Seyed Reza Aghili; Tahereh Shokohi; Mohammad Taghi Hedayati; Hossein Zarrinfar; Rasoul Mohammadi; Mohammad Javad Najafzadeh; Sadegh Khodavaisy; Ahmed Al-Harrasi; Mohammad Javan-Nikkhah; Reza Kachuei; Maryam Salimi; Mahsa Fattahi; Hamid Badali; Abdullah M S Al Hatmi; Mahdi Abastabar
Journal:  J Fungi (Basel)       Date:  2022-07-04

9.  Alginate nanoparticles as non-toxic delivery system for miltefosine in the treatment of candidiasis and cryptococcosis.

Authors:  Cristina de Castro Spadari; Fernanda Walt Mendes da Silva de Bastiani; Luciana Biagini Lopes; Kelly Ishida
Journal:  Int J Nanomedicine       Date:  2019-07-12
  9 in total

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