Literature DB >> 17225437

Acoustic response from adherent targeted contrast agents.

Shukui Zhao, Dustin E Kruse, Katherine W Ferrara, Paul A Dayton.   

Abstract

In ultrasonic molecular imaging, encapsulated micron-sized gas bubbles are tethered to a blood vessel wall by targeting ligands. A challenging problem is to detect the echoes from adherent microbubbles and distinguish them from echoes from nonadherent agents and tissue. Echoes from adherent contrast agents are observed to include a high amplitude at the fundamental frequency, and significantly different spectral shape compared with free agents (p <0.0003). Mechanisms for the observed acoustical difference and potential techniques to utilize these differences for molecular imaging are proposed.

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Year:  2006        PMID： 17225437      PMCID： PMC1780256          DOI： 10.1121/1.2364303

Source DB:  PubMed          Journal:  J Acoust Soc Am        ISSN： 0001-4966            Impact factor:   1.840


  10 in total

1.  Gas bubble pulsation in a semiconfined space subjected to ultrasound.

Authors:  B Krasovitski; E Kimmel
Journal:  J Acoust Soc Am       Date:  2001-03       Impact factor: 1.840

2.  Effect of coupled oscillations on microbubble behavior.

Authors:  John S Allen; Dustin E Kruse; Paul A Dayton; Katherine W Ferrara
Journal:  J Acoust Soc Am       Date:  2003-09       Impact factor: 1.840

3.  Targeted-microbubble binding selectively to GPIIb IIIa receptors of platelet thrombi.

Authors:  Patricia A Schumann; Jonathan P Christiansen; Rachel M Quigley; Thomas P McCreery; Robert H Sweitzer; Evan C Unger; Jonathan R Lindner; Terry O Matsunaga
Journal:  Invest Radiol       Date:  2002-11       Impact factor: 6.016

4.  Radiation-force assisted targeting facilitates ultrasonic molecular imaging.

Authors:  Shukui Zhao; Mark Borden; Susannah H Bloch; Dustin Kruse; Katherine W Ferrara; Paul A Dayton
Journal:  Mol Imaging       Date:  2004-07       Impact factor: 4.488

5.  Acoustic radiation force enhances targeted delivery of ultrasound contrast microbubbles: in vitro verification.

Authors:  Joshua J Rychak; Alexander L Klibanov; John A Hossack
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2005-03       Impact factor: 2.725

6.  Asymmetric oscillation of adherent targeted ultrasound contrast agents.

Authors:  Shukui Zhao; Katherine W Ferrara; Paul A Dayton
Journal:  Appl Phys Lett       Date:  2005-09-26       Impact factor: 3.791

7.  Optical and acoustical observations of the effects of ultrasound on contrast agents.

Authors:  P A Dayton; K E Morgan; A L Klibanov; G H Brandenburger; K W Ferrara
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  1999       Impact factor: 2.725

8.  Experimental and theoretical evaluation of microbubble behavior: effect of transmitted phase and bubble size.

Authors:  K E Morgan; J S Allen; P A Dayton; J E Chomas; A L Klibaov; K W Ferrara
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2000       Impact factor: 2.725

9.  In vitro characterization of a novel, tissue-targeted ultrasonic contrast system with acoustic microscopy.

Authors:  G M Lanza; R L Trousil; K D Wallace; J H Rose; C S Hall; M J Scott; J G Miller; P R Eisenberg; P J Gaffney; S A Wickline
Journal:  J Acoust Soc Am       Date:  1998-12       Impact factor: 1.840

10.  Noninvasive assessment of angiogenesis by ultrasound and microbubbles targeted to alpha(v)-integrins.

Authors:  Howard Leong-Poi; Jonathan Christiansen; Alexander L Klibanov; Sanjiv Kaul; Jonathan R Lindner
Journal:  Circulation       Date:  2003-01-28       Impact factor: 29.690
  10 in total
  11 in total

1.  Selective imaging of adherent targeted ultrasound contrast agents.

Authors:  S Zhao; D E Kruse; K W Ferrara; P A Dayton
Journal:  Phys Med Biol       Date:  2007-03-20       Impact factor: 3.609

2.  Tailoring the size distribution of ultrasound contrast agents: possible method for improving sensitivity in molecular imaging.

Authors:  Esra Talu; Kanaka Hettiarachchi; Shukui Zhao; Robert L Powell; Abraham P Lee; Marjorie L Longo; Paul A Dayton
Journal:  Mol Imaging       Date:  2007 Nov-Dec       Impact factor: 4.488

3.  A non-linear three-dimensional model for quantifying microbubble dynamics.

Authors:  Abhay V Patil; Paul Reynolds; John A Hossack
Journal:  J Acoust Soc Am       Date:  2010-02       Impact factor: 1.840

4.  Improving sensitivity in ultrasound molecular imaging by tailoring contrast agent size distribution: in vivo studies.

Authors:  Jason E Streeter; Ryan Gessner; Iman Miles; Paul A Dayton
Journal:  Mol Imaging       Date:  2010-04       Impact factor: 4.488

5.  Low-frequency ultrasound-mediated cytokine transfection enhances T cell recruitment at local and distant tumor sites.

Authors:  Tali Ilovitsh; Yi Feng; Josquin Foiret; Azadeh Kheirolomoom; Hua Zhang; Elizabeth S Ingham; Asaf Ilovitsh; Spencer K Tumbale; Brett Z Fite; Bo Wu; Marina N Raie; Nisi Zhang; Aris J Kare; Michael Chavez; Lei S Qi; Gadi Pelled; Dan Gazit; Ophir Vermesh; Idan Steinberg; Sanjiv S Gambhir; Katherine W Ferrara
Journal:  Proc Natl Acad Sci U S A       Date:  2020-05-19       Impact factor: 11.205

6.  Ultrasound for molecular imaging and therapy in cancer.

Authors:  Osamu F Kaneko; Jürgen K Willmann
Journal:  Quant Imaging Med Surg       Date:  2012-06

7.  Modeling of the acoustic response from contrast agent microbubbles near a rigid wall.

Authors:  Alexander A Doinikov; Shukui Zhao; Paul A Dayton
Journal:  Ultrasonics       Date:  2008-08-09       Impact factor: 2.890

8.  Effect of acoustic power on in vivo molecular imaging with targeted microbubbles: implications for low-mechanical index real-time imaging.

Authors:  Beat A Kaufmann; Chad L Carr; Todd Belcik; Aris Xie; Benjamin Kron; Qi Yue; Jonathan R Lindner
Journal:  J Am Soc Echocardiogr       Date:  2009-11-11       Impact factor: 5.251

9.  Fast microbubble dwell-time based ultrasonic molecular imaging approach for quantification and monitoring of angiogenesis in cancer.

Authors:  Marybeth A Pysz; Ismayil Guracar; Lu Tian; Jürgen K Willmann
Journal:  Quant Imaging Med Surg       Date:  2012-06-15

10.  Real-time targeted molecular imaging using singular value spectra properties to isolate the adherent microbubble signal.

Authors:  F William Mauldin; Ali H Dhanaliwala; Abhay V Patil; John A Hossack
Journal:  Phys Med Biol       Date:  2012-08-01       Impact factor: 3.609
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