Literature DB >> 17163249

Closer to an 'ideal inhaler' with the Easyhaler: an innovative dry powder inhaler.

Henry Chrystyn1.   

Abstract

The characteristics of an ideal inhaler are based around the design and formulation of the device, patient use and the clinical effect, together with concordance and patient preference. To ensure consistent drug delivery to the lungs, with regular adherence to the prescribed dosage regimen, it is essential that all these characteristics simultaneously interact to provide smooth and sustained therapeutic control affected only by the clinical status of the patient. The literature highlights that dose emission from an Easyhaler is fairly consistent irrespective of the inhalation technique used by patients of all age groups. Clinical studies have shown equivalence of this device to those frequently prescribed and that it is preferred by many patients. Although further research is required into the development of inhalation devices, the literature describing the Easyhaler dry powder inhaler indicates how an inhaler can closely meet the criteria for an ideal inhaler.

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Year:  2006        PMID: 17163249     DOI: 10.2165/00044011-200626040-00001

Source DB:  PubMed          Journal:  Clin Drug Investig        ISSN: 1173-2563            Impact factor:   2.859


  32 in total

1.  In-vitro intra- and inter-inhaler flow rate-dependent dosage emission from a combination of budesonide and eformoterol in a dry powder inhaler.

Authors:  W Tarsin; K H Assi; H Chrystyn
Journal:  J Aerosol Med       Date:  2004

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Journal:  Br Med J       Date:  1976-01-10

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Journal:  Arch Dis Child       Date:  1990-03       Impact factor: 3.791

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Journal:  J Aerosol Med       Date:  1995

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6.  Anatomy and physiology in delivery: can we define our targets?

Authors:  H Chrystyn
Journal:  Allergy       Date:  1999       Impact factor: 13.146

7.  Pharmaceutical transition to non-CFC pressurized metered dose inhalers.

Authors:  A Cripps; M Riebe; M Schulze; R Woodhouse
Journal:  Respir Med       Date:  2000-06       Impact factor: 3.415

8.  Is inhalation rate important for a dry powder inhaler? Using the In-Check Dial to identify these rates.

Authors:  H Chrystyn
Journal:  Respir Med       Date:  2003-02       Impact factor: 3.415

Review 9.  Measuring adherence to asthma medication regimens.

Authors:  C S Rand; R A Wise
Journal:  Am J Respir Crit Care Med       Date:  1994-02       Impact factor: 21.405

10.  Clinical comparison of inhaled budesonide delivered either via pressurized metered dose inhaler or Turbuhaler.

Authors:  T Engel; J H Heinig; H J Malling; B Scharling; K Nikander; F Madsen
Journal:  Allergy       Date:  1989-04       Impact factor: 13.146

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  7 in total

1.  Evaluation of in vitro and in vivo flow rate dependency of budesonide/formoterol Easyhaler(®).

Authors:  L Pekka Malmberg; Mark L Everard; Jussi Haikarainen; Satu Lähelmä
Journal:  J Aerosol Med Pulm Drug Deliv       Date:  2014-06-30       Impact factor: 2.849

Review 2.  Understanding Dry Powder Inhalers: Key Technical and Patient Preference Attributes.

Authors:  Mark L Levy; Will Carroll; José L Izquierdo Alonso; Claus Keller; Federico Lavorini; Lauri Lehtimäki
Journal:  Adv Ther       Date:  2019-09-02       Impact factor: 3.845

3.  Inhaler competence and patient satisfaction with Easyhaler®: results of two real-life multicentre studies in asthma and COPD.

Authors:  Gabriella Gálffy; Györgyi Mezei; Gyula Németh; Lilla Tamási; Veronika Müller; Olof Selroos; Marta Orosz
Journal:  Drugs R D       Date:  2013-09

4.  Switching patients from other inhaled corticosteroid devices to the Easyhaler(®): historical, matched-cohort study of real-life asthma patients.

Authors:  David Price; Vicky Thomas; Julie von Ziegenweidt; Shuna Gould; Catherine Hutton; Christine King
Journal:  J Asthma Allergy       Date:  2014-04-10

5.  Characteristics of reversible and nonreversible COPD and asthma and COPD overlap syndrome patients: an analysis of salbutamol Easyhaler data.

Authors:  Veronika Müller; Gabriella Gálffy; Márta Orosz; Zsuzsanna Kováts; Balázs Odler; Olof Selroos; Lilla Tamási
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2016-01-12

6.  Evaluation of the Efficiency of Single-Inhaler Combination Therapy with Budesonide/Formoterol Fumarate in Patients with Bronchial Asthma in Daily Clinical Practice.

Authors:  Michał Pirożyński; Piotr Hantulik; Agnieszka Almgren-Rachtan; Jerzy Chudek
Journal:  Adv Ther       Date:  2017-11-08       Impact factor: 3.845

7.  Dose uniformity of budesonide Easyhaler® under simulated real-life conditions and with low inspiration flow rates.

Authors:  Jussi Haikarainen; Paula Rytilä; Sirkku Roos; Sirpa Metsärinne; Anita Happonen
Journal:  Chron Respir Dis       Date:  2017-12-07       Impact factor: 2.444

  7 in total

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