Literature DB >> 6954081

Problems patients have using pressurized aerosol inhalers.

G K Crompton.   

Abstract

The use of pressurized aerosol inhalers was assessed in a total of 1173 out-patients attending hospital during a three month period. One hundred and thirty-five patients already being treated with drugs by inhalation were found to have a poor inhaler technique, even though most had received instruction on how to use a pressurized aerosol and were considered to be able to use one of these devices correctly. Eighty patients who had not used an inhaler before were found to be unable to use a pressurized aerosol efficiently after reading an instruction pamphlet or having the correct use of an aerosol demonstrated to them. Fifty-one percent of patients studied were observed to have difficulty in co-ordinating aerosol release with inspiration. In 24% the release of aerosol into the mouth caused a halt of inspiration and in a further 12% the aerosol was actuated into the mouth, but inspiration was achieved through the nose with no air being drawn in through the mouth. Twelve percent of patients already being treated with inhalers actuated the aerosol on two or more occasions during one inspiration.

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Year:  1982        PMID: 6954081

Source DB:  PubMed          Journal:  Eur J Respir Dis Suppl        ISSN: 0106-4347


  66 in total

1.  Results of a programme to improve house staff use of metered dose inhalers and spacers.

Authors:  M Lee-Wong; P H Mayo
Journal:  Postgrad Med J       Date:  2003-04       Impact factor: 2.401

Review 2.  Pulmonary drug delivery. Part II: the role of inhalant delivery devices and drug formulations in therapeutic effectiveness of aerosolized medications.

Authors:  N R Labiris; M B Dolovich
Journal:  Br J Clin Pharmacol       Date:  2003-12       Impact factor: 4.335

3.  Comparison of the efficacy and systemic effects of 4 mg and 8 mg formulations of salbutamol controlled release in patients with asthma.

Authors:  B J Lipworth; R A Clark; D P Dhillon; J B Palmer; D G McDevitt
Journal:  Eur J Clin Pharmacol       Date:  1990       Impact factor: 2.953

4.  Targeting asthma care in general practice using a morbidity index.

Authors:  K P Jones; I H Charlton; M Middleton; W J Preece; A P Hill
Journal:  BMJ       Date:  1992-05-23

Review 5.  Advances in metered dose inhaler technology: hardware development.

Authors:  Stephen W Stein; Poonam Sheth; P David Hodson; Paul B Myrdal
Journal:  AAPS PharmSciTech       Date:  2013-12-20       Impact factor: 3.246

6.  Early lung absorption profile of non-CFC salbutamol via small and large volume plastic spacer devices.

Authors:  B J Lipworth; D J Clark
Journal:  Br J Clin Pharmacol       Date:  1998-07       Impact factor: 4.335

Review 7.  Optimizing inhaled drug delivery in patients with asthma.

Authors:  C Jackson; B Lipworth
Journal:  Br J Gen Pract       Date:  1995-12       Impact factor: 5.386

Review 8.  Clinical pharmacokinetics of inhaled antimicrobials.

Authors:  Chris Stockmann; Jessica K Roberts; Venkata K Yellepeddi; Catherine M T Sherwin
Journal:  Clin Pharmacokinet       Date:  2015-05       Impact factor: 6.447

9.  Correlates of asthma morbidity in primary care.

Authors:  K P Jones; D J Bain; M Middleton; M A Mullee
Journal:  BMJ       Date:  1992-02-08

Review 10.  Patient preferences for inhaler devices in chronic obstructive pulmonary disease: experience with Respimat Soft Mist inhaler.

Authors:  Richard Hodder; David Price
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2009-10-19
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