Neuromagnetic evidence of a dynamic excitation pattern generating the N100 auditory response.

Evoked magnetic field recordings were used to localize multiple sources of the negative component of cortical responses to auditory stimuli. The negative cortical component of the auditory evoked response, often called the N100, has traditionally been of interest due to its sensitivity to both stimulation parameters and cognitive variables. Results indicate that this component appears to reflect spreading activation of adjacent cortical columns within the primary projection area of the temporal lobe, extending anteriorly for about 1 cm following the downward slope of the superior surface of the lobe.