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Literature DB >> 16816104

A brief history of RNAi: the silence of the genes.

Abstract

The use of the RNA interference (RNAi) pathway to eliminate gene products has greatly facilitated the understanding of gene function. Behind this remarkable pathway is an intricate network of proteins that ensures the degradation of the target mRNA. In this review, we explore the history of RNAi as well as highlighting recent discoveries.

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Year: 2006 PMID： 16816104 DOI： 10.1096/fj.06-6014rev

Source DB: PubMed Journal: FASEB J ISSN： 0892-6638 Impact factor: 5.191

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Cited

53 in total

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Review 5. Nanoparticulate RNA delivery systems in cancer.

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Review 6. ABC transporters and RNAi in Caenorhabditis elegans.

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7. RNA therapeutics: RNAi and antisense mechanisms and clinical applications.

Authors: Jessica Chery
Journal: Postdoc J Date: 2016-07

8. Investigation of molecular mechanism of chronic pain in the anterior cingulate cortex using genetically engineered mice.

Authors: Susan S Kim; Giannina Descalzi; Min Zhuo
Journal: Curr Genomics Date: 2010-03 Impact factor: 2.236

9. Estrogen Regulation of MicroRNA Expression.

Authors: Carolyn M Klinge
Journal: Curr Genomics Date: 2009-05 Impact factor: 2.236

10. Analysis of acyclic nucleoside modifications in siRNAs finds sensitivity at position 1 that is restored by 5'-terminal phosphorylation both in vitro and in vivo.

Authors: Denise M Kenski; Abby J Cooper; Jenny J Li; Aarron T Willingham; Henry J Haringsma; Tracy A Young; Nelly A Kuklin; Jeffrey J Jones; Mark T Cancilla; Daniel R McMasters; Melina Mathur; Alan B Sachs; W Michael Flanagan
Journal: Nucleic Acids Res Date: 2009-11-16 Impact factor: 16.971