Literature DB >> 16593568

A model of protein conformational substates.

D L Stein1.   

Abstract

Many proteins have been observed to exist in a large number of conformations that are believed to play an important role in their dynamics. A model of protein conformational substates that incorporates the ideas of frustration and disorder in analogy to glasses and spin glasses is proposed. Applications to x-ray diffraction, Mössbauer studies, and recombination experiments are discussed.

Entities:  

Year:  1985        PMID: 16593568      PMCID: PMC397848          DOI: 10.1073/pnas.82.11.3670

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  4 in total

1.  Temperature-dependent X-ray diffraction as a probe of protein structural dynamics.

Authors:  H Frauenfelder; G A Petsko; D Tsernoglou
Journal:  Nature       Date:  1979-08-16       Impact factor: 49.962

2.  Conformational substates in a protein: structure and dynamics of metmyoglobin at 80 K.

Authors:  H Hartmann; F Parak; W Steigemann; G A Petsko; D R Ponzi; H Frauenfelder
Journal:  Proc Natl Acad Sci U S A       Date:  1982-08       Impact factor: 11.205

3.  Dynamics of metmyoglobin crystals investigated by nuclear gamma resonance absorption.

Authors:  F Parak; E N Frolov; R L Mössbauer; V I Goldanskii
Journal:  J Mol Biol       Date:  1981-02-05       Impact factor: 5.469

4.  Dynamics of ligand binding to myoglobin.

Authors:  R H Austin; K W Beeson; L Eisenstein; H Frauenfelder; I C Gunsalus
Journal:  Biochemistry       Date:  1975-12-02       Impact factor: 3.162

  4 in total
  17 in total

1.  Radially softening diffusive motions in a globular protein.

Authors:  S Dellerue; A J Petrescu; J C Smith; M C Bellissent-Funel
Journal:  Biophys J       Date:  2001-09       Impact factor: 4.033

2.  Conformational model for ion permeation in membrane channels: a comparison with multi-ion models and applications to calcium channel permeability.

Authors:  S L Mironov
Journal:  Biophys J       Date:  1992-08       Impact factor: 4.033

3.  Conformational substates in azurin.

Authors:  D Ehrenstein; G U Nienhaus
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-15       Impact factor: 11.205

4.  Void distributions reveal structural link between jammed packings and protein cores.

Authors:  John D Treado; Zhe Mei; Lynne Regan; Corey S O'Hern
Journal:  Phys Rev E       Date:  2019-02       Impact factor: 2.529

5.  Fluorescence line narrowed spectra of Zn and metal-free cytochrome c.

Authors:  V Logovinsky; A D Kaposi; J M Vanderkooi
Journal:  J Fluoresc       Date:  1991-06       Impact factor: 2.217

6.  Temperature-derivative spectroscopy: a tool for protein dynamics.

Authors:  J Berendzen; D Braunstein
Journal:  Proc Natl Acad Sci U S A       Date:  1990-01       Impact factor: 11.205

7.  Forging tools for refining predicted protein structures.

Authors:  Xingcheng Lin; Nicholas P Schafer; Wei Lu; Shikai Jin; Xun Chen; Mingchen Chen; José N Onuchic; Peter G Wolynes
Journal:  Proc Natl Acad Sci U S A       Date:  2019-04-18       Impact factor: 11.205

8.  Terbium luminescence-lifetime heterogeneity and protein equilibrium conformational dynamics.

Authors:  R H Austin; D L Stein; J Wang
Journal:  Proc Natl Acad Sci U S A       Date:  1987-03       Impact factor: 11.205

9.  More than two pyrrole tautomers of mesoporphyrin stabilized by a protein. High resolution optical spectroscopic study.

Authors:  J Fidy; J M Vanderkooi; J Zollfrank; J Friedrich
Journal:  Biophys J       Date:  1992-02       Impact factor: 4.033

10.  Spin glasses and the statistical mechanics of protein folding.

Authors:  J D Bryngelson; P G Wolynes
Journal:  Proc Natl Acad Sci U S A       Date:  1987-11       Impact factor: 11.205

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