Literature DB >> 16585845

Focusing optics of a parallel beam CCD optical tomography apparatus for 3D radiation gel dosimetry.

Nikola Krstajić1, Simon J Doran.   

Abstract

Optical tomography of gel dosimeters is a promising and cost-effective avenue for quality control of radiotherapy treatments such as intensity-modulated radiotherapy (IMRT). Systems based on a laser coupled to a photodiode have so far shown the best results within the context of optical scanning of radiosensitive gels, but are very slow ( approximately 9 min per slice) and poorly suited to measurements that require many slices. Here, we describe a fast, three-dimensional (3D) optical computed tomography (optical-CT) apparatus, based on a broad, collimated beam, obtained from a high power LED and detected by a charged coupled detector (CCD). The main advantages of such a system are (i) an acquisition speed approximately two orders of magnitude higher than a laser-based system when 3D data are required, and (ii) a greater simplicity of design. This paper advances our previous work by introducing a new design of focusing optics, which take information from a suitably positioned focal plane and project an image onto the CCD. An analysis of the ray optics is presented, which explains the roles of telecentricity, focusing, acceptance angle and depth-of-field (DOF) in the formation of projections. A discussion of the approximation involved in measuring the line integrals required for filtered backprojection reconstruction is given. Experimental results demonstrate (i) the effect on projections of changing the position of the focal plane of the apparatus, (ii) how to measure the acceptance angle of the optics, and (iii) the ability of the new scanner to image both absorbing and scattering gel phantoms. The quality of reconstructed images is very promising and suggests that the new apparatus may be useful in a clinical setting for fast and accurate 3D dosimetry.

Mesh:

Year:  2006        PMID: 16585845     DOI: 10.1088/0031-9155/51/8/007

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  15 in total

1.  Preliminary commissioning investigations with the DMOS-RPC optical-CT Scanner.

Authors:  J Newton; A Thomas; G Ibbott; M Oldham
Journal:  J Phys Conf Ser       Date:  2010

2.  Fast, high-resolution 3D dosimetry utilizing a novel optical-CT scanner incorporating tertiary telecentric collimation.

Authors:  H S Sakhalkar; M Oldham
Journal:  Med Phys       Date:  2008-01       Impact factor: 4.071

3.  3D dosimetry by optical-CT scanning.

Authors:  Mark Oldham
Journal:  J Phys Conf Ser       Date:  2006

4.  An investigation of the accuracy of an IMRT dose distribution using two- and three-dimensional dosimetry techniques.

Authors:  Mark Oldham; Harshad Sakhalkar; Pengyi Guo; John Adamovics
Journal:  Med Phys       Date:  2008-05       Impact factor: 4.071

5.  Investigation into the feasibility of using PRESAGE/optical-CT dosimetry for the verification of gating treatments.

Authors:  Samuel L Brady; William E Brown; Corey G Clift; Sua Yoo; Mark Oldham
Journal:  Phys Med Biol       Date:  2010-03-26       Impact factor: 3.609

6.  A method to correct for spectral artifacts in optical-CT dosimetry.

Authors:  Andrew Thomas; Michael Pierquet; Kevin Jordan; Mark Oldham
Journal:  Phys Med Biol       Date:  2011-05-13       Impact factor: 3.609

7.  Preliminary Investigation of the Dosimetric Properties of 'RadGel'

Authors:  J R Newton; A Thomas; A Appleby; C Marsden; E A Christman; J G Wolodzko; M Oldham
Journal:  J Phys Conf Ser       Date:  2011

8.  A method to correct for stray light in telecentric optical-CT imaging of radiochromic dosimeters.

Authors:  Andrew Thomas; Joseph Newton; Mark Oldham
Journal:  Phys Med Biol       Date:  2011-06-30       Impact factor: 3.609

Review 9.  Polymer gel dosimetry.

Authors:  C Baldock; Y De Deene; S Doran; G Ibbott; A Jirasek; M Lepage; K B McAuley; M Oldham; L J Schreiner
Journal:  Phys Med Biol       Date:  2010-02-11       Impact factor: 3.609

10.  Improving the quantitative accuracy of optical-emission computed tomography by incorporating an attenuation correction: application to HIF1 imaging.

Authors:  E Kim; J Bowsher; A S Thomas; H Sakhalkar; M Dewhirst; M Oldham
Journal:  Phys Med Biol       Date:  2008-09-02       Impact factor: 3.609

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