OBJECTIVE: The objective of this study was to compare intracoronary attenuation on 16-row multislice computed tomography (16-MSCT) coronary angiography using 2 contrast materials (CM) with high iodine concentration. MATERIAL AND METHODS:Forty consecutive patients (29 male, 11 female; mean age, 61+/-11 years) with suspected coronary artery disease were randomized to 2 groups to receive 100 mL of either iopromide 370 (group 1: Ultravist 370, 370 mg iodine/mL; Schering AG, Berlin, Germany) or iomeprol 400 (group 2: Iomeron 400, 400 mg iodine/mL; Bracco Imaging SpA, Milan, Italy). Both CM were administered at a rate of 4 mL/s. All patients underwent 16-MSCT coronary angiography (Sensation 16; Siemens, Germany) with collimation 16 x 0.75 mm and rotation time 375 ms. The attenuation in Hounsfield units (HU) achieved after each CM was determined at regions of interest (ROIs) placed at the origin of coronary arteries and on the ascending aorta, descending aorta, and pulmonary artery. Differences in mean attenuation in the coronary arteries and on the ascending aorta, descending aorta, and pulmonary artery were evaluated using Student t test. RESULTS: The mean attenuation achieved at each anatomic site was consistently greater after iomeprol 400 than after iopromide 370. At the origin of coronary arteries, the mean attenuation after iomeprol 400 (340+/-53 HU) was greater (P<0.05) than that after iopromide 370 (313+/- 42 HU). Similar findings were noted for the mean attenuation in the ascending aorta, descending aorta, and pulmonary artery. CONCLUSION: The intravenous administration of iomeprol 400 provides higher attenuation of the coronary arteries and of the great arteries of the thorax as compared with iopromide 370 using the same injection parameters.
RCT Entities:
OBJECTIVE: The objective of this study was to compare intracoronary attenuation on 16-row multislice computed tomography (16-MSCT) coronary angiography using 2 contrast materials (CM) with high iodine concentration. MATERIAL AND METHODS: Forty consecutive patients (29 male, 11 female; mean age, 61+/-11 years) with suspected coronary artery disease were randomized to 2 groups to receive 100 mL of either iopromide 370 (group 1: Ultravist 370, 370 mg iodine/mL; Schering AG, Berlin, Germany) or iomeprol 400 (group 2: Iomeron 400, 400 mg iodine/mL; Bracco Imaging SpA, Milan, Italy). Both CM were administered at a rate of 4 mL/s. All patients underwent 16-MSCT coronary angiography (Sensation 16; Siemens, Germany) with collimation 16 x 0.75 mm and rotation time 375 ms. The attenuation in Hounsfield units (HU) achieved after each CM was determined at regions of interest (ROIs) placed at the origin of coronary arteries and on the ascending aorta, descending aorta, and pulmonary artery. Differences in mean attenuation in the coronary arteries and on the ascending aorta, descending aorta, and pulmonary artery were evaluated using Student t test. RESULTS: The mean attenuation achieved at each anatomic site was consistently greater after iomeprol 400 than after iopromide 370. At the origin of coronary arteries, the mean attenuation after iomeprol 400 (340+/-53 HU) was greater (P<0.05) than that after iopromide 370 (313+/- 42 HU). Similar findings were noted for the mean attenuation in the ascending aorta, descending aorta, and pulmonary artery. CONCLUSION: The intravenous administration of iomeprol 400 provides higher attenuation of the coronary arteries and of the great arteries of the thorax as compared with iopromide 370 using the same injection parameters.
Authors: Filippo Cademartiri; Erica Maffei; Anselmo Alessandro Palumbo; Roberto Malagò; Ludovico La Grutta; W Bob Meiijboom; Annachiara Aldrovandi; Michele Fusaro; Luigi Vignali; Alberto Menozzi; Valerio Brambilla; Paolo Coruzzi; Massimo Midiri; Miles A Kirchin; Nico R A Mollet; Gabriel P Krestin Journal: Eur Radiol Date: 2007-10-13 Impact factor: 5.315
Authors: S Keil; C Plumhans; F F Behrendt; M Das; S Stanzel; G Mühlenbruch; P Seidensticker; C Knackstedt; A H Mahnken; R W Günther; J E Wildberger Journal: Eur Radiol Date: 2008-04-08 Impact factor: 5.315
Authors: Florian F Behrendt; Hubertus Pietsch; Gregor Jost; Martin A Sieber; Sebastian Keil; Cedric Plumhans; Peter Seidensticker; Rolf W Günther; Andreas H Mahnken Journal: Eur Radiol Date: 2010-02-24 Impact factor: 5.315
Authors: Wen Jie Yang; Ke Min Chen; Bo Liu; Li Fang Pang; Huan Zhang; Zi Lai Pan; Fu Hua Yan Journal: Int J Cardiovasc Imaging Date: 2012-05-23 Impact factor: 2.357
Authors: Annemarieke Rutten; Matthijs F L Meijs; Alexander M de Vos; Peter R Seidensticker; Mathias Prokop Journal: Eur Radiol Date: 2010-03-20 Impact factor: 5.315