Literature DB >> 16413184

Schiff base conjugates of p-aminosalicylic acid as antimycobacterial agents.

Jayendra Patole1, Dipti Shingnapurkar, Subhash Padhye, Colin Ratledge.   

Abstract

Schiff base conjugates of p-aminosalicylic acid have been synthesized and characterized by elemental analysis, IR and (1)H NMR spectroscopy and cyclic voltammetry. Compounds containing hydroxyl-rich side chains show enhanced antimycobacterial activity against Mycobacterium smegmatis and Mycobacterium bovis BCG. Higher ClogP values and superior radical scavenging activities are thought to be the contributing factors for their enhanced antimycobacterial activities.

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Year:  2006        PMID： 16413184     DOI： 10.1016/j.bmcl.2005.12.035

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  12 in total

1.  2-[4-(4-Methoxyphenylcarbonyloxy)benzylidene]-6-dimethylaminomethyl cyclohexanone hydrochloride: a Mannich base which inhibits the growth of some drug-resistant strains of Mycobacterium tuberculosis.

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Journal:  Pharmazie       Date:  2010-11       Impact factor: 1.267

2.  Microwave-assisted synthesis of some hybrid molecules containing penicillanic acid or cephalosporanic acid moieties and investigation of their biological activities.

Authors:  Serap Basoglu; Serdar Ulker; Sengul Alpay-Karaoglu; Neslihan Demirbas
Journal:  Med Chem Res       Date:  2013-12-29       Impact factor: 1.965

3.  Synthesis Characterization and Antibacterial, Antifungal Activity of N-(Benzyl Carbamoyl or Carbamothioyl)-2-hydroxy Substituted Benzamide and 2-Benzyl Amino-Substituted Benzoxazines.

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Journal:  Int J Med Chem       Date:  2013-10-31

Review 4.  2-Amino-1,3,4-thiadiazole as a potential scaffold for promising antimicrobial agents.

Authors:  Georgeta Serban; Oana Stanasel; Sanda Bota; Eugenia Serban
Journal:  Drug Des Devel Ther       Date:  2018-05-31       Impact factor: 4.162

5.  Synthesis of new Schiff bases bearing 1,2,4-triazole, thiazolidine and chloroazetidine moieties and their pharmacological evaluation.

Authors:  Nadia G Kandile; Mansoura I Mohamed; Hind M Ismaeel
Journal:  J Enzyme Inhib Med Chem       Date:  2016-10-21       Impact factor: 5.051

6.  Synthesis of novel Schiff bases using 2-Amino-5-(3-fluoro-4-methoxyphenyl)thiophene-3-carbonitrile and 1,3-Disubstituted pyrazole-4-carboxaldehydes derivatives and their antimicrobial activity.

Authors:  Divyaraj Puthran; Boja Poojary; Nikil Purushotham; Nandam Harikrishna; Soukhyarani Gopal Nayak; Vinuta Kamat
Journal:  Heliyon       Date:  2019-08-26

7.  A second monoclinic polymorph of 4-[(E)-(4-benzyl-oxybenzyl-idene)amino]-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one.

Authors:  Rajni Kant; Vivek K Gupta; Kamini Kapoor; Prakash S Nayak; B K Sarojini; B Narayana
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-12-19

8.  Synthesis and Antibacterial Evaluation of New Thione Substituted 1,2,4-Triazole Schiff Bases as Novel Antimicrobial Agents.

Authors:  Karim Akbari Dilmaghani; Fazel Nasuhi Pur; Mahnaz Hatami Nezhad
Journal:  Iran J Pharm Res       Date:  2015       Impact factor: 1.696

9.  Equilibria in Aqueous Cobalt(II)-Reduced Schiff Base N-(2-hydroxybenzyl)alanine System: Chemical Characterization, Kinetic Analysis, Antimicrobial and Cytotoxic Properties.

Authors:  Magdalena Woźniczka; Manas Sutradhar; Armando J L Pombeiro; Mirosława Świątek; Marek Pająk; Joanna Gądek-Sobczyńska; Magdalena Chmiela; Weronika Gonciarz; Beata Pasternak; Aleksander Kufelnicki
Journal:  Molecules       Date:  2020-07-30       Impact factor: 4.411

10.  Aminosalicylic acid reduces ER stress and Schwann cell death induced by MPZ mutations.

Authors:  Eun Hyuk Chang; Won Min Mo; Hyun Myung Doo; Ji-Su Lee; Hwan Tae Park; Byung-Ok Choi; Young Bin Hong
Journal:  Int J Mol Med       Date:  2019-05-02       Impact factor: 4.101
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