Literature DB >> 16172999

Enhanced metabolic stability and protein-binding properties of artificial alpha helices derived from a hydrogen-bond surrogate: application to Bcl-xL.

Deyun Wang1, Wei Liao, Paramjit S Arora.   

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Year:  2005        PMID： 16172999      PMCID： PMC1351285          DOI： 10.1002/anie.200501603

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  20 in total

Review 1.  A view to a kill: ligands for Bcl-2 family proteins.

Authors:  Stacey E Rutledge; Jason W Chin; Alanna Schepartz
Journal:  Curr Opin Chem Biol       Date:  2002-08       Impact factor: 8.822

Review 2.  The Bcl-2 family: roles in cell survival and oncogenesis.

Authors:  Suzanne Cory; David C S Huang; Jerry M Adams
Journal:  Oncogene       Date:  2003-11-24       Impact factor: 9.867

3.  A highly stable short alpha-helix constrained by a main-chain hydrogen-bond surrogate.

Authors:  Ross N Chapman; Gianluca Dimartino; Paramjit S Arora
Journal:  J Am Chem Soc       Date:  2004-10-06       Impact factor: 15.419

4.  Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics.

Authors:  Anthony Letai; Michael C Bassik; Loren D Walensky; Mia D Sorcinelli; Solly Weiler; Stanley J Korsmeyer
Journal:  Cancer Cell       Date:  2002-09       Impact factor: 31.743

5.  Determination of the secondary structures of proteins by circular dichroism and optical rotatory dispersion.

Authors:  Y H Chen; J T Yang; H M Martinez
Journal:  Biochemistry       Date:  1972-10-24       Impact factor: 3.162

6.  Persistence of the alpha-helix stop signal in the S-peptide in trifluoroethanol solutions.

Authors:  J W Nelson; N R Kallenbach
Journal:  Biochemistry       Date:  1989-06-13       Impact factor: 3.162

7.  Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix.

Authors:  Loren D Walensky; Andrew L Kung; Iris Escher; Thomas J Malia; Scott Barbuto; Renee D Wright; Gerhard Wagner; Gregory L Verdine; Stanley J Korsmeyer
Journal:  Science       Date:  2004-09-03       Impact factor: 47.728

8.  Synthesis and helical structure of lactam bridged BH3 peptides derived from pro-apoptotic Bcl-2 family proteins.

Authors:  Bin Yang; Dongxiang Liu; Ziwei Huang
Journal:  Bioorg Med Chem Lett       Date:  2004-03-22       Impact factor: 2.823

9.  Development of a high-throughput fluorescence polarization assay for Bcl-x(L).

Authors:  Haichao Zhang; Paul Nimmer; Saul H Rosenberg; Shi-Chung Ng; Mary Joseph
Journal:  Anal Biochem       Date:  2002-08-01       Impact factor: 3.365

10.  Development of a potent Bcl-x(L) antagonist based on alpha-helix mimicry.

Authors:  Olaf Kutzki; Hyung Soon Park; Justin T Ernst; Brendan P Orner; Hang Yin; Andrew D Hamilton
Journal:  J Am Chem Soc       Date:  2002-10-09       Impact factor: 15.419
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  52 in total

1.  Extending foldamer design beyond α-helix mimicry: α/β-peptide inhibitors of vascular endothelial growth factor signaling.

Authors:  Holly S Haase; Kimberly J Peterson-Kaufman; Sheeny K Lan Levengood; James W Checco; William L Murphy; Samuel H Gellman
Journal:  J Am Chem Soc       Date:  2012-05-01       Impact factor: 15.419

2.  Application of ring-closing metathesis to Grb2 SH3 domain-binding peptides.

Authors:  Fa Liu; Alessio Giubellino; Philip C Simister; Wenjian Qian; Michael C Giano; Stephan M Feller; Donald P Bottaro; Terrence R Burke
Journal:  Biopolymers       Date:  2011       Impact factor: 2.505

Review 3.  Targeting recognition surfaces on natural proteins with peptidic foldamers.

Authors:  James W Checco; Samuel H Gellman
Journal:  Curr Opin Struct Biol       Date:  2016-07-05       Impact factor: 6.809

4.  Tightening up the structure, lighting up the pathway: Application of molecular constraints and light to manipulate protein folding, self-assembly and function.

Authors:  Beatrice N Markiewicz; Robert M Culik; Feng Gai
Journal:  Sci China Chem       Date:  2014-12       Impact factor: 9.445

5.  α/β-Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity in Living Cells.

Authors:  James W Checco; Erinna F Lee; Marco Evangelista; Nerida J Sleebs; Kelly Rogers; Anne Pettikiriarachchi; Nadia J Kershaw; Geoffrey A Eddinger; David G Belair; Julia L Wilson; Chelcie H Eller; Ronald T Raines; William L Murphy; Brian J Smith; Samuel H Gellman; W Douglas Fairlie
Journal:  J Am Chem Soc       Date:  2015-08-28       Impact factor: 15.419

6.  Universal peptidomimetics.

Authors:  Eunhwa Ko; Jing Liu; Lisa M Perez; Genliang Lu; Amber Schaefer; Kevin Burgess
Journal:  J Am Chem Soc       Date:  2010-12-23       Impact factor: 15.419

7.  Solid-phase synthesis of short α-helices stabilized by the hydrogen bond surrogate approach.

Authors:  Anupam Patgiri; Monica Z Menzenski; Andrew B Mahon; Paramjit S Arora
Journal:  Nat Protoc       Date:  2010-10-28       Impact factor: 13.491

8.  Evaluation of biologically relevant short alpha-helices stabilized by a main-chain hydrogen-bond surrogate.

Authors:  Deyun Wang; Kang Chen; John L Kulp Iii; Paramjit S Arora
Journal:  J Am Chem Soc       Date:  2006-07-19       Impact factor: 15.419

9.  Dynamical binding of hydrogen-bond surrogate derived Bak helices to antiapoptotic protein Bcl-xL.

Authors:  Ju Bao; Xiao Y Dong; John Z H Zhang; Paramjit S Arora
Journal:  J Phys Chem B       Date:  2009-03-19       Impact factor: 2.991

Review 10.  Protein Domain Mimics as Modulators of Protein-Protein Interactions.

Authors:  Nicholas Sawyer; Andrew M Watkins; Paramjit S Arora
Journal:  Acc Chem Res       Date:  2017-05-31       Impact factor: 22.384
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