BACKGROUND: Microfocus computed tomography (muCT) is an emerging technique owing to its speed, full three-dimensional information, and nondestructive properties. PURPOSE: The aim of this study was to explore the efficacy of a muCT system (Philips HOMX 161, Philips Medical Systems GmbH, Hamburg, Germany) for visualization of the bone structure around screw-type titanium implants by comparing muCT images with their histologic homologues. MATERIALS AND METHODS: Eight screw-type titanium implants were placed in the femoral condyles of two goats. After the excised implant-bone specimens were embedded in resin, three-dimensional muCT of the excised implant and bone specimens was performed. Histologic sections were subsequently made. A total of 150 histologic sections were matched with muCT images. RESULTS: Bone trabeculae were clearly visible on the muCT scans. However, bone close to the implant or present in the apical surface features of the implant could not be detected. The overall matching between muCT scans (slices) and the histologic sections was 89%. CONCLUSION: Investigation of trabecular bone around titanium implants by muCT can be considered highly reliable for determining trabecular bone parameters, with the exception of measuring direct bone-to-implant contact.
BACKGROUND: Microfocus computed tomography (muCT) is an emerging technique owing to its speed, full three-dimensional information, and nondestructive properties. PURPOSE: The aim of this study was to explore the efficacy of a muCT system (Philips HOMX 161, Philips Medical Systems GmbH, Hamburg, Germany) for visualization of the bone structure around screw-type titanium implants by comparing muCT images with their histologic homologues. MATERIALS AND METHODS: Eight screw-type titanium implants were placed in the femoral condyles of two goats. After the excised implant-bone specimens were embedded in resin, three-dimensional muCT of the excised implant and bone specimens was performed. Histologic sections were subsequently made. A total of 150 histologic sections were matched with muCT images. RESULTS: Bone trabeculae were clearly visible on the muCT scans. However, bone close to the implant or present in the apical surface features of the implant could not be detected. The overall matching between muCT scans (slices) and the histologic sections was 89%. CONCLUSION: Investigation of trabecular bone around titanium implants by muCT can be considered highly reliable for determining trabecular bone parameters, with the exception of measuring direct bone-to-implant contact.
Authors: Ioannis Papantoniou; Maarten Sonnaert; Liesbet Geris; Frank P Luyten; Jan Schrooten; Greet Kerckhofs Journal: Tissue Eng Part C Methods Date: 2013-10-19 Impact factor: 3.056
Authors: Po-Chun Chang; Yang-Jo Seol; Noboru Kikuchi; Steven A Goldstein; William V Giannobile Journal: J Biomed Mater Res B Appl Biomater Date: 2010-07 Impact factor: 3.368
Authors: Po-Chun Chang; Yang-Jo Seol; Steven A Goldstein; William V Giannobile Journal: Int J Oral Maxillofac Implants Date: 2013 Jan-Feb Impact factor: 2.804
Authors: Manal M Shalabi; Johannes G C Wolke; Vincent M J I Cuijpers; John A Jansen Journal: J Mater Sci Mater Med Date: 2007-06-09 Impact factor: 3.896
Authors: Yan Huang; Jeroen Van Dessel; Maarten Depypere; Mostafa EzEldeen; Alexandru Andrei Iliescu; Emanuela Dos Santos; Ivo Lambrichts; Xin Liang; Reinhilde Jacobs Journal: Bone Res Date: 2014-06-10 Impact factor: 13.567