Literature DB >> 15821187

Lung cancer detection in patients with airflow obstruction identified in a primary care outpatient practice.

Joel J Bechtel1, William A Kelley, Teresa A Coons, M Gerry Klein, Daniel D Slagel, Thomas L Petty.   

Abstract

INTRODUCTION: This prospective study describes a community-based lung cancer identification project focusing on high-risk patients who receive general care in a primary care outpatient practice. Within 1 calendar year, a simple questionnaire was completed in 1,296 patients > 50 years old to identify 430 patients at high risk of lung cancer (smoking, family history of aerodigestive tract cancer, or occupational exposures). Spirometric abnormalities were found in 126 of these patients.
METHODS: Chest posteroanterior radiographs, thoracic CT scans, and sputum cytology were offered to subjects with airflow obstruction (n = 126). Eighty-eight patients underwent all tests. Thirty-eight patients refused or could not consent in a timely fashion.
RESULTS: Six cancers were found in the screened group, and all were treated. Two more cancers were found in the nonscreened patients with airflow obstruction. Both were treated by surgical resection or radiation therapy. Costs per cancer found were $11,925 per patient.
CONCLUSIONS: Case finding in high-risk patients in a primary care population can be accomplished at a relatively low cost.

Entities:  

Mesh:

Year:  2005        PMID: 15821187     DOI: 10.1378/chest.127.4.1140

Source DB:  PubMed          Journal:  Chest        ISSN: 0012-3692            Impact factor:   9.410


  11 in total

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Authors:  Peter J Mazzone; Tarek Mekhail
Journal:  Curr Oncol Rep       Date:  2007-07       Impact factor: 5.075

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5.  Inhaled corticosteroids and risk of lung cancer among patients with chronic obstructive pulmonary disease.

Authors:  Tanyalak Parimon; Jason W Chien; Chris L Bryson; Mary B McDonell; Edmunds M Udris; David H Au
Journal:  Am J Respir Crit Care Med       Date:  2006-12-21       Impact factor: 21.405

Review 6.  Chronic obstructive pulmonary disease (COPD) and lung cancer: common pathways for pathogenesis.

Authors:  Brielle A Parris; Hannah E O'Farrell; Kwun M Fong; Ian A Yang
Journal:  J Thorac Dis       Date:  2019-10       Impact factor: 2.895

7.  Autofluorescence bronchoscopy for lung cancer surveillance based on risk assessment.

Authors:  Gregory Loewen; Nachimuthu Natarajan; Dongfeng Tan; Enriqueta Nava; Donald Klippenstein; Martin Mahoney; Michael Cummings; Mary Reid
Journal:  Thorax       Date:  2006-11-13       Impact factor: 9.139

8.  Overwhelming support among urban Irish COPD patients for lung cancer screening by low-dose CT scan.

Authors:  M Pallin; S Walsh; M F O'Driscoll; C Murray; A Cahalane; L Brown; M Carter; P Mitchell; T J McDonnell; M W Butler
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9.  Genetic evidence linking lung cancer and COPD: a new perspective.

Authors:  Robert P Young; Raewyn J Hopkins; Gregory D Gamble; Carol Etzel; Randa El-Zein; James D Crapo
Journal:  Appl Clin Genet       Date:  2011-07-18

10.  Lung Screen Uptake Trial: results from a single lung cancer screening round.

Authors:  Mamta Ruparel; Samantha L Quaife; Jennifer L Dickson; Carolyn Horst; Sophie Tisi; Helen Hall; Magali Taylor; Asia Ahmed; Penny Shaw; Stephen Burke; May-Jan Soo; Arjun Nair; Anand Devaraj; Karen Sennett; Stephen W Duffy; Neal Navani; Angshu Bhowmik; David R Baldwin; Sam M Janes
Journal:  Thorax       Date:  2020-08-05       Impact factor: 9.139

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