Literature DB >> 15571868

Synthesis and antifungal activity of cholesterol-hydrazone derivatives.

Céline Loncle1, Jean Michel Brunel, Nicolas Vidal, Michel Dherbomez, Yves Letourneux.   

Abstract

A series of hydrazones synthesized from various cholesterol derivatives were evaluated for their in vitro antimicrobial properties against human pathogens. The activity was highly dependent on the structure of the different compounds involved. The best results have been obtained with tosylhydrazone cholesterol derivatives 8 and 9 exhibiting activities against Candida albicans (CIP 1663-80) at a concentration of 1.5 microg/ml.

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Year:  2004        PMID： 15571868     DOI： 10.1016/j.ejmech.2004.07.005

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN： 0223-5234            Impact factor:   6.514


  37 in total

1.  In vivo metabolism of 2-[1'-phenyl-3'-(3-chlorophenyl)-2'-propenylyden]hydrazino-3-methyl-4(3H)-quinazolinone in rats.

Authors:  Bedia Koçyiğit Kaymakçioğlu; Yasemin Aktan; Sibel Süzen; Nesrin Gökhan; Semra Koyunoğlu; Kevser Erol; Akgül Yeşilada; Sevim Rollas
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2005 Oct-Dec       Impact factor: 2.441

2.  Study of Binding Properties Between Two New Ibuprofen and Naproxen Based Acyl Hydrazone Derivatives and Trypsin.

Authors:  Elmas Gökoğlu; Esra Yılmaz; Esra Gökoğlu; Ayşe Uzgören Baran
Journal:  J Fluoresc       Date:  2016-01       Impact factor: 2.217

3.  Computer-aided design of novel antibacterial 3-hydroxypyridine-4-ones: application of QSAR methods based on the MOLMAP approach.

Authors:  Razieh Sabet; Afshin Fassihi; Bahram Hemmateenejad; Lotfollah Saghaei; Ramin Miri; Maryam Gholami
Journal:  J Comput Aided Mol Des       Date:  2012-03-28       Impact factor: 3.686

4.  HPLC analysis of in vivo metabolites of 4-nitrobenzoic acid [(5-nitro-2-thiopheneyl)methylene]hydrazide in rats.

Authors:  Bedia Koçyiğit-Kaymakçioğlu; Seda Unsalan; S Güniz Küçükgüzel; Göksel Sener; Sevim Rollas
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2007 Oct-Dec       Impact factor: 2.441

5.  1,5-Bis-[1-(2-hy-droxy-phen-yl)ethyl-idene]carbonohydrazide dimethyl-formamide monosolvate.

Authors:  Lingyun Du; Wenkang Zhang
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-09-30

6.  1-[1-(4-Chloro-phen-yl)ethyl-idene]carbono-hydrazide.

Authors:  Lingyun Du; Lei Du; Shuhao Wang
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-08-12

Review 7.  Biological activities of hydrazone derivatives.

Authors:  Sevim Rollas; S Güniz Küçükgüzel
Journal:  Molecules       Date:  2007-08-17       Impact factor: 4.411

8.  1-(1-Phenyl-ethyl-idene)carbonohydrazide.

Authors:  Yan Qiao; Xiuping Ju; Zhiqing Gao; Lingqian Kong
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-09-30

9.  Novel Thiochromanone Derivatives Containing a Sulfonyl Hydrazone Moiety: Design, Synthesis, and Bioactivity Evaluation.

Authors:  Lu Yu; Jiyan Chi; Lingling Xiao; Jie Li; Zhangfei Tang; Shuming Tan; Pei Li
Journal:  Molecules       Date:  2021-05-14       Impact factor: 4.411

10.  Synthesis of New Functionally Substituted 9-Azabicyclo[4.2.1]nona-2,4,7-trienes by Cobalt(I)-Catalyzed [6π + 2π]-Cycloaddition of N-Carbocholesteroxyazepine to Alkynes.

Authors:  Gulnara N Kadikova; Vladimir A D'yakonov; Usein M Dzhemilev
Journal:  Molecules       Date:  2021-05-14       Impact factor: 4.411
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