Literature DB >> 15520799

Reductionism and complexity in molecular biology. Scientists now have the tools to unravel biological and overcome the limitations of reductionism.

Marc H V Van Regenmortel1.   

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Year:  2004        PMID: 15520799      PMCID: PMC1299179          DOI: 10.1038/sj.embor.7400284

Source DB:  PubMed          Journal:  EMBO Rep        ISSN: 1469-221X            Impact factor:   8.807


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  31 in total

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3.  Biological complexity emerges from the ashes of genetic reductionism.

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Journal:  J Mol Recognit       Date:  2004 May-Jun       Impact factor: 2.137

4.  Bio-ontologies-fast and furious.

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5.  Towards a multi-site synthetic vaccine to foot-and-mouth disease: addition of discontinuous site peptide mimic increases the neutralization response in immunized animals.

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Journal:  Vaccine       Date:  2004-09-09       Impact factor: 3.641

Review 6.  Biotechnology: identifying advances from the hype.

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Review 7.  Conformational changes associated with protein-protein interactions.

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Review 8.  The atomic mobility component of protein antigenicity.

Authors:  J A Tainer; E D Getzoff; Y Paterson; A J Olson; R A Lerner
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10.  Correlation between segmental mobility and the location of antigenic determinants in proteins.

Authors:  E Westhof; D Altschuh; D Moras; A C Bloomer; A Mondragon; A Klug; M H Van Regenmortel
Journal:  Nature       Date:  1984 Sep 13-19       Impact factor: 49.962

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  79 in total

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2.  Western science and traditional knowledge. Despite their variations, different forms of knowledge can learn from each other.

Authors:  Fulvio Mazzocchi
Journal:  EMBO Rep       Date:  2006-05       Impact factor: 8.807

3.  ARC: automated resource classifier for agglomerative functional classification of prokaryotic proteins using annotation texts.

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Journal:  J Biosci       Date:  2007-08       Impact factor: 1.826

4.  Emergent decision-making in biological signal transduction networks.

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5.  Complexity in biology. Exceeding the limits of reductionism and determinism using complexity theory.

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6.  The evolution of biology. A shift towards the engineering of prediction-generating tools and away from traditional research practice.

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7.  The reductionist paradox: are the laws of chemistry and physics sufficient for the discovery of new drugs?

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Journal:  J Comput Aided Mol Des       Date:  2011-06-23       Impact factor: 3.686

Review 8.  From Reductionism to Holism: Toward a More Complete View of Development Through Genome Engineering.

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Review 9.  So what do we really mean when we say that systems biology is holistic?

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Journal:  PLoS One       Date:  2009-12-09       Impact factor: 3.240

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