Literature DB >> 11731767

Realism in drug discovery-could Cassandra be right?

D F Horrobin.   

Abstract

Mesh：

Year:  2001        PMID： 11731767     DOI： 10.1038/nbt1201-1099

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN： 1087-0156            Impact factor:   54.908


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  12 in total

1.  Drug repositioning using disease associated biological processes and network analysis of drug targets.

Authors:  Sachin Mathur; Deendayal Dinakarpandian
Journal:  AMIA Annu Symp Proc       Date:  2011-10-22

Review 2.  Diagnosing the decline in pharmaceutical R&D efficiency.

Authors:  Jack W Scannell; Alex Blanckley; Helen Boldon; Brian Warrington
Journal:  Nat Rev Drug Discov       Date:  2012-03-01       Impact factor: 84.694

3.  Advances in Nuclear Magnetic Resonance for Drug Discovery.

Authors:  Robert Powers
Journal:  Expert Opin Drug Discov       Date:  2009-10-01       Impact factor: 6.098

4.  Reductionism and complexity in molecular biology. Scientists now have the tools to unravel biological and overcome the limitations of reductionism.

Authors:  Marc H V Van Regenmortel
Journal:  EMBO Rep       Date:  2004-11       Impact factor: 8.807

Review 5.  Strategic challenges in neurotherapeutic pharmaceutical development.

Authors:  Christopher C Gallen
Journal:  NeuroRx       Date:  2004-01

6.  The evolution of biology. A shift towards the engineering of prediction-generating tools and away from traditional research practice.

Authors:  Lawrence Kelley; Michael Scott
Journal:  EMBO Rep       Date:  2008-11-14       Impact factor: 8.807

Review 7.  The discovery of first-in-class drugs: origins and evolution.

Authors:  Jörg Eder; Richard Sedrani; Christian Wiesmann
Journal:  Nat Rev Drug Discov       Date:  2014-07-18       Impact factor: 84.694

Review 8.  In silico methods for drug repurposing and pharmacology.

Authors:  Rachel A Hodos; Brian A Kidd; Khader Shameer; Ben P Readhead; Joel T Dudley
Journal:  Wiley Interdiscip Rev Syst Biol Med       Date:  2016-04-15

Review 9.  Using pharmacogenetics and pharmacogenomics in the treatment of psychiatric disorders: some ethical and economic considerations.

Authors:  Katherine I Morley; Wayne D Hall
Journal:  J Mol Med (Berl)       Date:  2003-11-04       Impact factor: 4.599

10.  When Quality Beats Quantity: Decision Theory, Drug Discovery, and the Reproducibility Crisis.

Authors:  Jack W Scannell; Jim Bosley
Journal:  PLoS One       Date:  2016-02-10       Impact factor: 3.240
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