Literature DB >> 15487729

Development of a 30-week-pregnant female tomographic model from computed tomography (CT) images for Monte Carlo organ dose calculations.

Chengyu Shi1, X George Xu.   

Abstract

Assessment of radiation dose and risk to a pregnant woman and her fetus is an important task in radiation protection. Although tomographic models for male and female patients of different ages have been developed using medical images, such models for pregnant women had not been developed to date. This paper reports the construction of a partial-body model of a pregnant woman from a set of computed tomography (CT) images. The patient was 30 weeks into pregnancy, and the CT scan covered the portion of the body from above liver to below pubic symphysis in 70 slices. The thickness for each slice is 7 mm, and the image resolution is 512x512 pixels in a 48 cm x 48 cm field; thus, the voxel size is 6.15 mm3. The images were segmented to identify 34 major internal organs and tissues considered sensitive to radiation. Even though the masses are noticeably different from other models, the three-dimensional visualization verified the segmentation and its suitability for Monte Carlo calculations. The model has been implemented into a Monte Carlo code, EGS4-VLSI (very large segmented images), for the calculations of radiation dose to a pregnant woman. The specific absorbed fraction (SAF) results for internal photons were compared with those from a stylized model. Small and large differences were found, and the differences can be explained by mass differences and by the relative geometry differences between the source and the target organs. The research provides the radiation dosimetry community with the first voxelized tomographic model of a pregnant woman, opening the door to future dosimetry studies.

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Year:  2004        PMID: 15487729     DOI: 10.1118/1.1778836

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  14 in total

Review 1.  Current status and new horizons in Monte Carlo simulation of X-ray CT scanners.

Authors:  Habib Zaidi; Mohammad Reza Ay
Journal:  Med Biol Eng Comput       Date:  2007-07-05       Impact factor: 2.602

2.  Foetal dose conversion coefficients for ICRP-compliant pregnant models from idealised proton exposures.

Authors:  Valery Taranenko; X George Xu
Journal:  Radiat Prot Dosimetry       Date:  2009-02-26       Impact factor: 0.972

3.  SAF values for internal photon emitters calculated for the RPI-P pregnant-female models using Monte Carlo methods.

Authors:  C Y Shi; X George Xu; Michael G Stabin
Journal:  Med Phys       Date:  2008-07       Impact factor: 4.071

4.  Specific absorbed fractions for internal electron emitters derived for a set of anatomically realistic reference pregnant female models.

Authors:  Bingqi Guo; X George Xu; Chengyu Shi
Journal:  Radiat Prot Dosimetry       Date:  2009-09-18       Impact factor: 0.972

5.  MCAT to XCAT: The Evolution of 4-D Computerized Phantoms for Imaging Research: Computer models that take account of body movements promise to provide evaluation and improvement of medical imaging devices and technology.

Authors:  W Paul Segars; Benjamin M W Tsui
Journal:  Proc IEEE Inst Electr Electron Eng       Date:  2009-12       Impact factor: 10.961

Review 6.  An exponential growth of computational phantom research in radiation protection, imaging, and radiotherapy: a review of the fifty-year history.

Authors:  X George Xu
Journal:  Phys Med Biol       Date:  2014-08-21       Impact factor: 3.609

7.  The UF family of hybrid phantoms of the developing human fetus for computational radiation dosimetry.

Authors:  Matthew R Maynard; John W Geyer; John P Aris; Roger Y Shifrin; Wesley Bolch
Journal:  Phys Med Biol       Date:  2011-07-15       Impact factor: 3.609

8.  The development, validation and application of a multi-detector CT (MDCT) scanner model for assessing organ doses to the pregnant patient and the fetus using Monte Carlo simulations.

Authors:  J Gu; B Bednarz; P F Caracappa; X G Xu
Journal:  Phys Med Biol       Date:  2009-04-08       Impact factor: 3.609

9.  A feasibility study to calculate unshielded fetal doses to pregnant patients in 6-MV photon treatments using Monte Carlo methods and anatomically realistic phantoms.

Authors:  Bryan Bednarz; X George Xu
Journal:  Med Phys       Date:  2008-07       Impact factor: 4.071

10.  Radiation dose to the fetus for pregnant patients undergoing multidetector CT imaging: Monte Carlo simulations estimating fetal dose for a range of gestational age and patient size.

Authors:  Erin Angel; Clinton V Wellnitz; Mitchell M Goodsitt; Nazanin Yaghmai; John J DeMarco; Christopher H Cagnon; James W Sayre; Dianna D Cody; Donna M Stevens; Andrew N Primak; Cynthia H McCollough; Michael F McNitt-Gray
Journal:  Radiology       Date:  2008-10       Impact factor: 11.105

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