Literature DB >> 14704207

Distinguishing the hitchhiking and background selection models.

Hideki Innan1, Wolfgang Stephan.   

Abstract

A simple method to distinguish hitchhiking and background selection is proposed. It is based on the observation that these models make different predictions about the average level of nucleotide diversity in regions of low recombination. The method is applied to data from Drosophila melanogaster and two highly selfing tomato species.

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Year:  2003        PMID: 14704207      PMCID: PMC1462879     

Source DB:  PubMed          Journal:  Genetics        ISSN: 0016-6731            Impact factor:   4.562


  18 in total

1.  Joint effects of genetic hitchhiking and background selection on neutral variation.

Authors:  Y Kim; W Stephan
Journal:  Genetics       Date:  2000-07       Impact factor: 4.562

Review 2.  Adaptive hitchhiking effects on genome variability.

Authors:  P Andolfatto
Journal:  Curr Opin Genet Dev       Date:  2001-12       Impact factor: 5.578

Review 3.  Molecular population genetics.

Authors:  Magnus Nordborg; Hideki Innan
Journal:  Curr Opin Plant Biol       Date:  2002-02       Impact factor: 7.834

4.  A diffusion approximation for selection and drift in a subdivided population.

Authors:  Joshua L Cherry; John Wakeley
Journal:  Genetics       Date:  2003-01       Impact factor: 4.562

5.  Selective sweeps in the presence of interference among partially linked loci.

Authors:  Yuseob Kim; Wolfgang Stephan
Journal:  Genetics       Date:  2003-05       Impact factor: 4.562

6.  The pattern of polymorphism on human chromosome 21.

Authors:  Hideki Innan; Badri Padhukasahasram; Magnus Nordborg
Journal:  Genome Res       Date:  2003-06       Impact factor: 9.043

7.  Selection at linked sites in the partial selfer Caenorhabditis elegans.

Authors:  Asher D Cutter; Bret A Payseur
Journal:  Mol Biol Evol       Date:  2003-04-02       Impact factor: 16.240

8.  Regions of lower crossing over harbor more rare variants in African populations of Drosophila melanogaster.

Authors:  P Andolfatto; M Przeworski
Journal:  Genetics       Date:  2001-06       Impact factor: 4.562

9.  The hitch-hiking effect of a favourable gene.

Authors:  J M Smith; J Haigh
Journal:  Genet Res       Date:  1974-02       Impact factor: 1.588

10.  Single nucleotide polymorphisms and recombination rate in humans.

Authors:  M W Nachman
Journal:  Trends Genet       Date:  2001-09       Impact factor: 11.639

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  26 in total

1.  Patterns of neutral diversity under general models of selective sweeps.

Authors:  Graham Coop; Peter Ralph
Journal:  Genetics       Date:  2012-06-19       Impact factor: 4.562

Review 2.  Genetic hitchhiking versus background selection: the controversy and its implications.

Authors:  Wolfgang Stephan
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2010-04-27       Impact factor: 6.237

3.  Natural selection shapes nucleotide polymorphism across the genome of the nematode Caenorhabditis briggsae.

Authors:  Asher D Cutter; Jae Young Choi
Journal:  Genome Res       Date:  2010-05-27       Impact factor: 9.043

4.  A pseudohitchhiking model of X vs. autosomal diversity.

Authors:  Andrea J Betancourt; Yuseob Kim; H Allen Orr
Journal:  Genetics       Date:  2004-12       Impact factor: 4.562

5.  DNA sequence polymorphism and divergence at the erect wing and suppressor of sable loci of Drosophila melanogaster and D. simulans.

Authors:  John M Braverman; Brian P Lazzaro; Montserrat Aguadé; Charles H Langley
Journal:  Genetics       Date:  2005-06-08       Impact factor: 4.562

6.  The relationship of nucleotide polymorphism, recombination rate and selection in wild tomato species.

Authors:  Kerstin Roselius; Wolfgang Stephan; Thomas Städler
Journal:  Genetics       Date:  2005-08-05       Impact factor: 4.562

Review 7.  Population genetic inference from genomic sequence variation.

Authors:  John E Pool; Ines Hellmann; Jeffrey D Jensen; Rasmus Nielsen
Journal:  Genome Res       Date:  2010-01-12       Impact factor: 9.043

8.  Population genetic analysis of shotgun assemblies of genomic sequences from multiple individuals.

Authors:  Ines Hellmann; Yuan Mang; Zhiping Gu; Peter Li; Francisco M de la Vega; Andrew G Clark; Rasmus Nielsen
Journal:  Genome Res       Date:  2008-04-14       Impact factor: 9.043

Review 9.  Evolutionary consequences of self-fertilization in plants.

Authors:  Stephen I Wright; Susan Kalisz; Tanja Slotte
Journal:  Proc Biol Sci       Date:  2013-06-07       Impact factor: 5.349

10.  Hitchhiking effects of recurrent beneficial amino acid substitutions in the Drosophila melanogaster genome.

Authors:  Peter Andolfatto
Journal:  Genome Res       Date:  2007-11-07       Impact factor: 9.043

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