Literature DB >> 11525814

Single nucleotide polymorphisms and recombination rate in humans.

M W Nachman1.   

Abstract

Levels of heterozygosity for single nucleotide polymorphisms vary by more than one order of magnitude in different regions of the human genome. Regional differences in the rate of recombination explain a substantial fraction of the variation in levels of nucleotide polymorphism, consistent with the widespread action of natural selection at the molecular level.

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Year:  2001        PMID: 11525814     DOI: 10.1016/s0168-9525(01)02409-x

Source DB:  PubMed          Journal:  Trends Genet        ISSN: 0168-9525            Impact factor:   11.639


  114 in total

1.  Complex signatures of natural selection at the Duffy blood group locus.

Authors:  Martha T Hamblin; Emma E Thompson; Anna Di Rienzo
Journal:  Am J Hum Genet       Date:  2001-12-20       Impact factor: 11.025

2.  The signature of positive selection at randomly chosen loci.

Authors:  Molly Przeworski
Journal:  Genetics       Date:  2002-03       Impact factor: 4.562

3.  Levels of DNA polymorphism vary with mating system in the nematode genus caenorhabditis.

Authors:  Andrew Graustein; John M Gaspar; James R Walters; Michael F Palopoli
Journal:  Genetics       Date:  2002-05       Impact factor: 4.562

4.  DNA recombination. Recombination initiation maps of individual human genomes.

Authors:  Florencia Pratto; Kevin Brick; Pavel Khil; Fatima Smagulova; Galina V Petukhova; R Daniel Camerini-Otero
Journal:  Science       Date:  2014-11-14       Impact factor: 47.728

5.  A neutral explanation for the correlation of diversity with recombination rates in humans.

Authors:  Ines Hellmann; Ingo Ebersberger; Susan E Ptak; Svante Pääbo; Molly Przeworski
Journal:  Am J Hum Genet       Date:  2003-05-08       Impact factor: 11.025

6.  A coalescent model of recombination hotspots.

Authors:  Carsten Wiuf; David Posada
Journal:  Genetics       Date:  2003-05       Impact factor: 4.562

7.  Distinguishing the hitchhiking and background selection models.

Authors:  Hideki Innan; Wolfgang Stephan
Journal:  Genetics       Date:  2003-12       Impact factor: 4.562

8.  Genomic effects of nucleotide substitutions in Drosophila simulans.

Authors:  Andrew D Kern; Corbin D Jones; David J Begun
Journal:  Genetics       Date:  2002-12       Impact factor: 4.562

9.  Extensive linkage disequilibrium, a common 16.7-kilobase deletion, and evidence of balancing selection in the human protocadherin alpha cluster.

Authors:  James P Noonan; Jun Li; Loan Nguyen; Chenier Caoile; Mark Dickson; Jane Grimwood; Jeremy Schmutz; Marcus W Feldman; Richard M Myers
Journal:  Am J Hum Genet       Date:  2003-02-07       Impact factor: 11.025

10.  Speciation as a positive feedback loop between postzygotic and prezygotic barriers to gene flow.

Authors:  Maria R Servedio; Glenn-Peter Saetre
Journal:  Proc Biol Sci       Date:  2003-07-22       Impact factor: 5.349

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