Literature DB >> 14602692

Implications of carrier identification in newborn screening for cystic fibrosis.

E P Parsons1, A J Clarke, D M Bradley.   

Abstract

OBJECTIVE: To investigate the psychosocial implications for families whose infant was identified as a cystic fibrosis carrier by newborn screening.
DESIGN: Prospective psychosocial assessment.
SETTING: Primary care. STUDY: (a) families of an affected infant identified by screening (n = 9); (b) families of a carrier infant identified by screening (n = 10). CONTROL: group of mothers from the general population (n = 82).
INTERVENTIONS: Questionnaires and semistructured interviews. MAIN OUTCOME MEASURES: Attitude to screening, assessments of the mother/baby relationship, anxiety, wellbeing.
RESULTS: All families were in favour of screening, with no evidence that the mother/baby relationship, anxiety or wellbeing had been adversely affected. Parents, however, did identify problems in terms of the service delivery protocol and genetic counselling practice.
CONCLUSION: Six months after disclosure, carrier identification was not perceived by parents to be problematic.

Entities:  

Mesh:

Year:  2003        PMID: 14602692      PMCID: PMC1763227          DOI: 10.1136/fn.88.6.f467

Source DB:  PubMed          Journal:  Arch Dis Child Fetal Neonatal Ed        ISSN: 1359-2998            Impact factor:   5.747


  10 in total

1.  Psychological and social consequences of community carrier screening programme for cystic fibrosis.

Authors:  E K Watson; E S Mayall; J Lamb; J Chapple; R Williamson
Journal:  Lancet       Date:  1992-07-25       Impact factor: 79.321

2.  Disclosure of Duchenne muscular dystrophy after newborn screening.

Authors:  E Parsons; D Bradley; A Clarke
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3.  Benefits and burdens of genetic carrier identification.

Authors:  J K Williams; D L Schutte
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4.  Newborn screening for Duchenne muscular dystrophy: a psychosocial study.

Authors:  E P Parsons; A J Clarke; K Hood; E Lycett; D M Bradley
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2002-03       Impact factor: 5.747

5.  The impact of population based screening for carriers of cystic fibrosis.

Authors:  H Bekker; G Denniss; M Modell; M Bobrow; T Marteau
Journal:  J Med Genet       Date:  1994-05       Impact factor: 6.318

6.  Mother-child relationship--FIRST score.

Authors:  E M Salariya; J I Cater
Journal:  J Adv Nurs       Date:  1984-11       Impact factor: 3.187

7.  Cystic fibrosis newborn screening: impact of early screening results on parenting stress.

Authors:  M A Baroni; Y E Anderson; E Mischler
Journal:  Pediatr Nurs       Date:  1997 Mar-Apr

8.  Barriers to carrier testing for adult cystic fibrosis sibs: the importance of not knowing.

Authors:  J H Fanos; J P Johnson
Journal:  Am J Med Genet       Date:  1995-10-23

9.  Prenatal screening for cystic fibrosis.

Authors:  M E Mennie; A Gilfillan; M Compton; L Curtis; W A Liston; I Pullen; D A Whyte; D J Brock
Journal:  Lancet       Date:  1992-07-25       Impact factor: 79.321

10.  The development of a six-item short-form of the state scale of the Spielberger State-Trait Anxiety Inventory (STAI).

Authors:  T M Marteau; H Bekker
Journal:  Br J Clin Psychol       Date:  1992-09
  10 in total
  18 in total

Review 1.  How risk is perceived, constructed and interpreted by clients in clinical genetics, and the effects on decision making: systematic review.

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Journal:  J Genet Couns       Date:  2007-10-30       Impact factor: 2.537

Review 2.  Newborn screening for cystic fibrosis: do we need a second IRT?

Authors:  J F Price
Journal:  Arch Dis Child       Date:  2006-03       Impact factor: 3.791

3.  Newborn screening for cystic fibrosis: techniques and strategies.

Authors:  Bridget Wilcken
Journal:  J Inherit Metab Dis       Date:  2007-05-12       Impact factor: 4.982

4.  Questioning the consensus: managing carrier status results generated by newborn screening.

Authors:  Fiona Alice Miller; Jason Scott Robert; Robin Z Hayeems
Journal:  Am J Public Health       Date:  2008-12-04       Impact factor: 9.308

Review 5.  A systematic review of the effects of disclosing carrier results generated through newborn screening.

Authors:  R Z Hayeems; J P Bytautas; F A Miller
Journal:  J Genet Couns       Date:  2008-10-28       Impact factor: 2.537

6.  Predictive genetic testing in children: where are we now? An overview and a UK perspective.

Authors:  Anneke Lucassen; Jonathan Montgomery
Journal:  Fam Cancer       Date:  2010-03       Impact factor: 2.375

7.  Cystic fibrosis newborn screening: distribution of blood immunoreactive trypsinogen concentrations in hypertrypsinemic neonates.

Authors:  Valentina Paracchini; Manuela Seia; Sara Raimondi; Lucy Costantino; Patrizia Capasso; Luigi Porcaro; Carla Colombo; Domenico A Coviello; Tiziana Mariani; Emanuela Manzoni; Monica Sangiovanni; Carlo Corbetta
Journal:  JIMD Rep       Date:  2011-11-04

8.  Informing parents about positive newborn screen results: parents' recommendations.

Authors:  Natalie Salm; Elena Yetter; Audrey Tluczek
Journal:  J Child Health Care       Date:  2012-09-14       Impact factor: 1.979

9.  Genetic testing in children and young people.

Authors:  Michael Parker
Journal:  Fam Cancer       Date:  2009-07-30       Impact factor: 2.375

10.  Disparities in current and future childhood and newborn carrier identification.

Authors:  Melissa Noke; Alison Wearden; Sarah Peters; Fiona Ulph
Journal:  J Genet Couns       Date:  2014-07-11       Impact factor: 2.537

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