Literature DB >> 14072177

AFLATOXIN B2: CHEMICAL IDENTITY AND BIOLOGICAL ACTIVITY.

S B CHANG, M M ABDEL-KADER, E L WICK, G N WOGAN.   

Abstract

Aflatoxin B(2), a blue-fluorescent metabolite of Aspergillus flavus, was isolated from cultures grown on crushed wheat. Chemical structure of the compound was elucidated as dihydroaflatoxin B(1). Biological activity was determined in day-old male white Pekin ducklings. The criteria of activity were reduction in growth and liver size and the extent of bile-duct hyperplasia.

Entities:  

Keywords:  ASPERGILLUS; BILE DUCTS; EXPERIMENTAL LAB STUDY; LIVER; POULTRY; TOXICOLOGIC REPORT; TOXINS AND ANTITOXINS

Mesh:

Substances:

Year:  1963        PMID: 14072177     DOI: 10.1126/science.142.3596.1191

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  20 in total

1.  THE DETERMINATION OF AFLATOXINS IN COTTONSEED PRODUCTS.

Authors:  W A PONS; L A GOLDBLATT
Journal:  J Am Oil Chem Soc       Date:  1965-06       Impact factor: 1.849

2.  Effect of Aeration on Growth and Aflatoxin Production by Aspergillus flavus in Submerged Culture.

Authors:  A W Hayes; N D Davis; U L Diener
Journal:  Appl Microbiol       Date:  1966-11

3.  The distribution of tritium-labeled aflatoxin B1, dihydro-aflatoxin B1, and tetrahydrodesoxoaflatoxin B1 in liver cells cultured in vitro from the chicken embryo.

Authors:  K Terao; M Yamazaki; K Miyaki
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1972-12-29

Review 4.  Aflatoxin formation by Aspergillus flavus.

Authors:  C W Hesseltine; O L Shotwell; J J Ellis; R D Stubblefield
Journal:  Bacteriol Rev       Date:  1966-12

Review 5.  Chemical nature and biological effects of the aflatoxins.

Authors:  G N Wogan
Journal:  Bacteriol Rev       Date:  1966-06

6.  Separation and purification of aflatoxins B1, B2, G1 and G2, and comparison of semi-synthetic aflatoxins B2 and G2 with naturally-occurring aflatoxins B2 and G2.

Authors:  J V Rodricks
Journal:  J Am Oil Chem Soc       Date:  1969-03       Impact factor: 1.849

7.  Occurrence of aflatoxins and aflatoxin-producing strains of Aspergillus spp. in soybeans.

Authors:  G A Bean; J A Schillinger; W L Klarman
Journal:  Appl Microbiol       Date:  1972-09

8.  PRODUCTION OF AFLATOXINS IN SUBMERGED CULTURE.

Authors:  R I MATELES; J C ADYE
Journal:  Appl Microbiol       Date:  1965-03

9.  The interaction of aflatoxin B1 with polynucleotides and its effect on ribonucleic acid polymerase.

Authors:  A M King; B H Nicholson
Journal:  Biochem J       Date:  1969-10       Impact factor: 3.857

10.  Production of aflatoxin on rice.

Authors:  O L Shotwell; C W Hesseltine; R D Stubblefield; W G Sorenson
Journal:  Appl Microbiol       Date:  1966-05
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