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Literature DB >> 13776497

A new synthetic compound with antituberculous activity in mice: ethambutol (dextro-2,2'-(ethylenediimino)-di-l-butanol).

J P THOMAS, C O BAUGHN, R G WILKINSON, R G SHEPHERD.

Abstract

Entities: Chemical Species

Keywords: ANTITUBERCULAR AGENTS/pharmacology

Mesh：

Substances：

Year: 1961 PMID： 13776497 DOI： 10.1164/arrd.1961.83.6.891

Source DB: PubMed Journal: Am Rev Respir Dis ISSN： 0003-0805

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22 in total

1. [MYCOBACTERIUM OR NOCARDIA PELLEGRINO?].

Authors: S E JUHASZ; R BOENICKE
Journal: Beitr Klin Tuberk Spezif Tuberkuloseforsch Date: 1965-03-31

2. Inhibition of synthesis of arabinogalactan by ethambutol in Mycobacterium smegmatis.

Authors: K Takayama; J O Kilburn
Journal: Antimicrob Agents Chemother Date: 1989-09 Impact factor: 5.191

Review 3. Natural products, small molecules, and genetics in tuberculosis drug development.

Authors: Maria-Teresa Gutierrez-Lugo; Carole A Bewley
Journal: J Med Chem Date: 2008-04-05 Impact factor: 7.446

Review 4. Tuberculosis Drug Development: History and Evolution of the Mechanism-Based Paradigm.

Authors: Sumit Chakraborty; Kyu Y Rhee
Journal: Cold Spring Harb Perspect Med Date: 2015-04-15 Impact factor: 6.915

Review 5. The Mycobacterial Cell Wall--Peptidoglycan and Arabinogalactan.

Authors: Luke J Alderwick; James Harrison; Georgina S Lloyd; Helen L Birch
Journal: Cold Spring Harb Perspect Med Date: 2015-03-27 Impact factor: 6.915

6. The embAB genes of Mycobacterium avium encode an arabinosyl transferase involved in cell wall arabinan biosynthesis that is the target for the antimycobacterial drug ethambutol.

Authors: A E Belanger; G S Besra; M E Ford; K Mikusová; J T Belisle; P J Brennan; J M Inamine
Journal: Proc Natl Acad Sci U S A Date: 1996-10-15 Impact factor: 11.205

A new synthetic compound with antituberculous activity in mice: ethambutol (dextro-2,2'-(ethylenediimino)-di-l-butanol).

1. [MYCOBACTERIUM OR NOCARDIA PELLEGRINO?].

2. Inhibition of synthesis of arabinogalactan by ethambutol in Mycobacterium smegmatis.

Review 3. Natural products, small molecules, and genetics in tuberculosis drug development.

Review 4. Tuberculosis Drug Development: History and Evolution of the Mechanism-Based Paradigm.

Review 5. The Mycobacterial Cell Wall--Peptidoglycan and Arabinogalactan.

6. The embAB genes of Mycobacterium avium encode an arabinosyl transferase involved in cell wall arabinan biosynthesis that is the target for the antimycobacterial drug ethambutol.

Review 7. Pulmonary tuberculosis: evolution of modern therapy.

8. [Dynamics of experimental tuberculous lesions in guinea pigs under the influence of ethambutol therapy].

9. Inhibition by ethambutol of mycolic acid transfer into the cell wall of Mycobacterium smegmatis.

10. Mode of action of ethambutol.