Literature DB >> 18393405

Natural products, small molecules, and genetics in tuberculosis drug development.

Maria-Teresa Gutierrez-Lugo1, Carole A Bewley.   

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Year:  2008        PMID： 18393405      PMCID： PMC6260804          DOI： 10.1021/jm070719i

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  63 in total

1.  Use of a flexible cassette method to generate a double unmarked Mycobacterium tuberculosis tlyA plcABC mutant by gene replacement.

Authors:  T Parish; N G Stoker
Journal:  Microbiology       Date:  2000-08       Impact factor: 2.777

2.  The actinomycins and their importance in the treatment of tumors in animals and man. Historical background.

Authors:  H B WOODRUFF; S A WAKSMAN
Journal:  Ann N Y Acad Sci       Date:  1960-10-05       Impact factor: 5.691

3.  The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism: novel insights into drug mechanisms of action.

Authors:  Helena I M Boshoff; Timothy G Myers; Brent R Copp; Michael R McNeil; Michael A Wilson; Clifton E Barry
Journal:  J Biol Chem       Date:  2004-07-09       Impact factor: 5.157

Review 4.  Changing funding patterns in tuberculosis.

Authors:  Stefan H E Kaufmann; Shreemanta K Parida
Journal:  Nat Med       Date:  2007-03       Impact factor: 53.440

5.  Identification of a new antitubercular drug candidate, SQ109, from a combinatorial library of 1,2-ethylenediamines.

Authors:  Marina Protopopova; Colleen Hanrahan; Boris Nikonenko; Rowena Samala; Ping Chen; Jackie Gearhart; Leo Einck; Carol A Nacy
Journal:  J Antimicrob Chemother       Date:  2005-09-19       Impact factor: 5.790

Review 6.  Mycothiol biochemistry.

Authors:  Gerald L Newton; Robert C Fahey
Journal:  Arch Microbiol       Date:  2002-09-03       Impact factor: 2.552

7.  Mycobacterium tuberculosis gene expression during adaptation to stationary phase and low-oxygen dormancy.

Authors:  M I Voskuil; K C Visconti; G K Schoolnik
Journal:  Tuberculosis (Edinb)       Date:  2004       Impact factor: 3.131

8.  Stationary phase gene expression of Mycobacterium tuberculosis following a progressive nutrient depletion: a model for persistent organisms?

Authors:  Tobias Hampshire; Shamit Soneji; Joanna Bacon; Brian W James; Jason Hinds; Ken Laing; Richard A Stabler; Philip D Marsh; Philip D Butcher
Journal:  Tuberculosis (Edinb)       Date:  2004       Impact factor: 3.131

9.  Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.

Authors:  S T Cole; R Brosch; J Parkhill; T Garnier; C Churcher; D Harris; S V Gordon; K Eiglmeier; S Gas; C E Barry; F Tekaia; K Badcock; D Basham; D Brown; T Chillingworth; R Connor; R Davies; K Devlin; T Feltwell; S Gentles; N Hamlin; S Holroyd; T Hornsby; K Jagels; A Krogh; J McLean; S Moule; L Murphy; K Oliver; J Osborne; M A Quail; M A Rajandream; J Rogers; S Rutter; K Seeger; J Skelton; R Squares; S Squares; J E Sulston; K Taylor; S Whitehead; B G Barrell
Journal:  Nature       Date:  1998-06-11       Impact factor: 49.962

10.  Prioritizing genomic drug targets in pathogens: application to Mycobacterium tuberculosis.

Authors:  Samiul Hasan; Sabine Daugelat; P S Srinivasa Rao; Mark Schreiber
Journal:  PLoS Comput Biol       Date:  2006-06-09       Impact factor: 4.475
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  15 in total

1.  Examination of mechanism of N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-α-D-glucopyranoside deacetylase (MshB) reveals unexpected role for dynamic tyrosine.

Authors:  Xinyi Huang; Marcy Hernick
Journal:  J Biol Chem       Date:  2012-02-07       Impact factor: 5.157

2.  Inhibition of siderophore biosynthesis by 2-triazole substituted analogues of 5'-O-[N-(salicyl)sulfamoyl]adenosine: antibacterial nucleosides effective against Mycobacterium tuberculosis.

Authors:  Amol Gupte; Helena I Boshoff; Daniel J Wilson; João Neres; Nicholas P Labello; Ravindranadh V Somu; Chengguo Xing; Clifton E Barry; Courtney C Aldrich
Journal:  J Med Chem       Date:  2008-12-11       Impact factor: 7.446

3.  Total synthesis and biological evaluation of transvalencin Z.

Authors:  Kathryn M Nelson; Christine E Salomon; Courtney C Aldrich
Journal:  J Nat Prod       Date:  2012-05-22       Impact factor: 4.050

4.  The activity and cofactor preferences of N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) change depending on environmental conditions.

Authors:  Xinyi Huang; Evren Kocabas; Marcy Hernick
Journal:  J Biol Chem       Date:  2011-04-20       Impact factor: 5.157

5.  Toward the total synthesis of elisapterosin B: A Hg(OTf)(2)-promoted diastereoselective intramolecular Friedel-Crafts alkylation reaction.

Authors:  Weijiang Ying; Charles L Barnes; Michael Harmata
Journal:  Tetrahedron Lett       Date:  2011-01-12       Impact factor: 2.415

6.  Evaluation of flavonoid and resveratrol chemical libraries reveals abyssinone II as a promising antibacterial lead.

Authors:  Dianqing Sun; Julian G Hurdle; Robin Lee; Richard Lee; Mark Cushman; John M Pezzuto
Journal:  ChemMedChem       Date:  2012-07-30       Impact factor: 3.466

7.  Benzothiazines in synthesis. A formal total synthesis of pseudopteroxazole.

Authors:  Michael Harmata; Zhengxin Cai; Yugang Chen
Journal:  J Org Chem       Date:  2009-08-07       Impact factor: 4.354

8.  Dequalinium, a new inhibitor of Mycobacterium tuberculosis mycothiol ligase identified by high-throughput screening.

Authors:  Maria-Teresa Gutierrez-Lugo; Heather Baker; Joseph Shiloach; Helena Boshoff; Carole A Bewley
Journal:  J Biomol Screen       Date:  2009-06-12

9.  Antimycobacterial and HIV-1 Reverse Transcriptase Activity of Julianaceae and Clusiaceae Plant Species from Mexico.

Authors:  Rocio Gómez-Cansino; Clara Inés Espitia-Pinzón; María Guadalupe Campos-Lara; Silvia Laura Guzmán-Gutiérrez; Erika Segura-Salinas; Gabriela Echeverría-Valencia; Laura Torras-Claveria; Xochitl Marisol Cuevas-Figueroa; Ricardo Reyes-Chilpa
Journal:  Evid Based Complement Alternat Med       Date:  2015-04-23       Impact factor: 2.629

10.  Synthesis, structure-activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives.

Authors:  Li Feng; Marcus M Maddox; Md Zahidul Alam; Lissa S Tsutsumi; Gagandeep Narula; David F Bruhn; Xiaoqian Wu; Shayna Sandhaus; Robin B Lee; Charles J Simmons; Yuk-Ching Tse-Dinh; Julian G Hurdle; Richard E Lee; Dianqing Sun
Journal:  J Med Chem       Date:  2014-10-07       Impact factor: 7.446
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