Literature DB >> 12937007

A new TEM-derived extended-spectrum beta-lactamase (TEM-91) with an R164C substitution at the omega-loop confers ceftazidime resistance.

Hiroshi Kurokawa1, Naohiro Shibata, Yohei Doi, Keigo Shibayama, Kazunari Kamachi, Tetsuya Yagi, Yoshichika Arakawa.   

Abstract

A new plasmid-mediated TEM-derived extended-spectrum beta-lactamase, TEM-91, was identified in a ceftazidime-resistant (MIC, >128 microg per ml) Escherichia coli strain isolated in 1996 in Japan. TEM-91 has three amino acid substitutions, R164C, M184T, and E240K, compared with TEM-1 penicillinase. The isoelectric point (pI), K(m), and k(cat) of TEM-91 for ceftazidime were 5.7, 179 microM, and 29.0 s(-1), respectively. The K(i) of clavulanic acid for ceftazidime hydrolysis was 30.3 nM.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12937007      PMCID： PMC182605          DOI： 10.1128/AAC.47.9.2981-2983.2003

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  25 in total

1.  Worldwide proliferation of carbapenem-resistant gram-negative bacteria.

Authors:  H Kurokawa; T Yagi; N Shibata; K Shibayama; Y Arakawa
Journal:  Lancet       Date:  1999-09-11       Impact factor: 79.321

2.  A new SHV-derived extended-spectrum beta-lactamase (SHV-24) that hydrolyzes ceftazidime through a single-amino-acid substitution (D179G) in the -loop.

Authors:  H Kurokawa; T Yagi; N Shibata; K Shibayama; K Kamachi; Y Arakawa
Journal:  Antimicrob Agents Chemother       Date:  2000-06       Impact factor: 5.191

Review 3.  beta-Lactamases of increasing clinical importance.

Authors:  K Bush
Journal:  Curr Pharm Des       Date:  1999-11       Impact factor: 3.116

4.  Updated sequence information and proposed nomenclature for bla(TEM) genes and their promoters.

Authors:  V Leflon-Guibout; B Heym; M Nicolas-Chanoine
Journal:  Antimicrob Agents Chemother       Date:  2000-11       Impact factor: 5.191

Review 5.  New approaches in the treatment of bacterial infections.

Authors:  K Bush; M Macielag
Journal:  Curr Opin Chem Biol       Date:  2000-08       Impact factor: 8.822

6.  A standard numbering scheme for the class A beta-lactamases.

Authors:  R P Ambler; A F Coulson; J M Frère; J M Ghuysen; B Joris; M Forsman; R C Levesque; G Tiraby; S G Waley
Journal:  Biochem J       Date:  1991-05-15       Impact factor: 3.857

7.  TEM-72, a new extended-spectrum beta-lactamase detected in Proteus mirabilis and Morganella morganii in Italy.

Authors:  M Perilli; B Segatore; M R de Massis; M L Riccio; C Bianchi; A Zollo; G M Rossolini; G Amicosante
Journal:  Antimicrob Agents Chemother       Date:  2000-09       Impact factor: 5.191

8.  Characterization of a new extended-spectrum beta-lactamase (TEM-87) isolated in Proteus mirabilis during an Italian survey.

Authors:  Mariagrazia Perilli; Bernardetta Segatore; Maria Rosaria De Massis; Nicola Franceschini; Ciro Bianchi; Gian Maria Rossolini; Gianfranco Amicosante
Journal:  Antimicrob Agents Chemother       Date:  2002-03       Impact factor: 5.191

9.  Characterization of a novel plasmid-mediated cephalosporinase (CMY-9) and its genetic environment in an Escherichia coli clinical isolate.

Authors:  Yohei Doi; Naohiro Shibata; Keigo Shibayama; Kazunari Kamachi; Hiroshi Kurokawa; Keiko Yokoyama; Tetsuya Yagi; Yoshichika Arakawa
Journal:  Antimicrob Agents Chemother       Date:  2002-08       Impact factor: 5.191

10.  Chromosomal beta-lactamases of Enterobacter cloacae are responsible for resistance to third-generation cephalosporins.

Authors:  A H Seeberg; R M Tolxdorff-Neutzling; B Wiedemann
Journal:  Antimicrob Agents Chemother       Date:  1983-06       Impact factor: 5.191
View more
  7 in total

1.  New TEM-derived extended-spectrum beta-lactamase and its genomic context in plasmids from Salmonella enterica serovar derby isolates from Uruguay.

Authors:  Rafael Vignoli; Nicolas F Cordeiro; Virginia García; María Inés Mota; Laura Betancor; Pablo Power; José A Chabalgoity; Felipe Schelotto; Gabriel Gutkind; Juan A Ayala
Journal:  Antimicrob Agents Chemother       Date:  2006-02       Impact factor: 5.191

2.  Exploring the Role of the Ω-Loop in the Evolution of Ceftazidime Resistance in the PenA β-Lactamase from Burkholderia multivorans, an Important Cystic Fibrosis Pathogen.

Authors:  Krisztina M Papp-Wallace; Scott A Becka; Magdalena A Taracila; Elise T Zeiser; Julian A Gatta; John J LiPuma; Robert A Bonomo
Journal:  Antimicrob Agents Chemother       Date:  2017-01-24       Impact factor: 5.191

3.  Practical methods using boronic acid compounds for identification of class C beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli.

Authors:  Tetsuya Yagi; Jun-ichi Wachino; Hiroshi Kurokawa; Satowa Suzuki; Kunikazu Yamane; Yohei Doi; Naohiro Shibata; Haru Kato; Keigo Shibayama; Yoshichika Arakawa
Journal:  J Clin Microbiol       Date:  2005-06       Impact factor: 5.948

4.  In vitro and in vivo activities of novel 6-methylidene penems as beta-lactamase inhibitors.

Authors:  William J Weiss; Peter J Petersen; Timothy M Murphy; Luanna Tardio; Youjun Yang; Patricia A Bradford; Aranapakam M Venkatesan; Takao Abe; Takeshi Isoda; Ado Mihira; Hideki Ushirogochi; Tsuyoshi Takasake; Steve Projan; John O'Connell; Tarek S Mansour
Journal:  Antimicrob Agents Chemother       Date:  2004-12       Impact factor: 5.191

5.  Activity of ceftazidime/avibactam against isogenic strains of Escherichia coli containing KPC and SHV β-lactamases with single amino acid substitutions in the Ω-loop.

Authors:  Marisa L Winkler; Krisztina M Papp-Wallace; Robert A Bonomo
Journal:  J Antimicrob Chemother       Date:  2015-05-08       Impact factor: 5.790

6.  Pyrosequencing using the single-nucleotide polymorphism protocol for rapid determination of TEM- and SHV-type extended-spectrum beta-lactamases in clinical isolates and identification of the novel beta-lactamase genes blaSHV-48, blaSHV-105, and blaTEM-155.

Authors:  C Hal Jones; Alexey Ruzin; Margareta Tuckman; Melissa A Visalli; Peter J Petersen; Patricia A Bradford
Journal:  Antimicrob Agents Chemother       Date:  2008-12-15       Impact factor: 5.191

7.  High adaptability of the omega loop underlies the substrate-spectrum-extension evolution of a class A β-lactamase, PenL.

Authors:  Hyojeong Yi; Jin Myung Choi; Junghyun Hwang; Fabio Prati; Thinh-Phat Cao; Sung Haeng Lee; Heenam Stanley Kim
Journal:  Sci Rep       Date:  2016-11-09       Impact factor: 4.379
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.