Literature DB >> 10959772

New approaches in the treatment of bacterial infections.

K Bush1, M Macielag.   

Abstract

Recently, several new drugs for the treatment of bacterial infections have been developed. Quinupristin/dalfopristin, moxifloxacin and gatifloxacin have been approved throughout the world for clinical use. Levofloxacin has been approved for the treatment of community-acquired pneumonia caused by penicillin-resistant Streptococcus pnuemoniae. The Food and Drug Administration has approved linezolid for clinical use, and new drug applications for gemifloxacin and telithromycin were filed. Other new targets have surfaced in the quest for novel antibacterial agents.

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Year:  2000        PMID： 10959772     DOI： 10.1016/s1367-5931(00)00106-x

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN： 1367-5931            Impact factor:   8.822


  8 in total

1.  A new TEM-derived extended-spectrum beta-lactamase (TEM-91) with an R164C substitution at the omega-loop confers ceftazidime resistance.

Authors:  Hiroshi Kurokawa; Naohiro Shibata; Yohei Doi; Keigo Shibayama; Kazunari Kamachi; Tetsuya Yagi; Yoshichika Arakawa
Journal:  Antimicrob Agents Chemother       Date:  2003-09       Impact factor: 5.191

2.  In vitro antimicrobial, antioxidant and cytotoxic properties of Streptomyces lavendulae strain SCA5.

Authors:  Pachaiyappan Saravana Kumar; Naif Abdullah Al-Dhabi; Veeramuthu Duraipandiyan; Chandrasekar Balachandran; Panthagani Praveen Kumar; Savarimuthu Ignacimuthu
Journal:  BMC Microbiol       Date:  2014-11-30       Impact factor: 3.605

3.  Phenolic compounds as antioxidants and chemopreventive drugs from Streptomyces cellulosae strain TES17 isolated from rhizosphere of Camellia sinensis.

Authors:  Riveka Rani; Saroj Arora; Jeevanjot Kaur; Rajesh Kumari Manhas
Journal:  BMC Complement Altern Med       Date:  2018-03-09       Impact factor: 3.659

4.  Discovery of novel inhibitors of Streptococcus pneumoniae based on the virtual screening with the homology-modeled structure of histidine kinase (VicK).

Authors:  Nan Li; Fei Wang; Siqiang Niu; Ju Cao; Kaifeng Wu; Youqiang Li; Nanlin Yin; Xuemei Zhang; Weiliang Zhu; Yibing Yin
Journal:  BMC Microbiol       Date:  2009-06-27       Impact factor: 3.605

5.  Cytotoxicity and antioxidant activity of 5-(2,4-dimethylbenzyl)pyrrolidin-2-one extracted from marine Streptomyces VITSVK5 spp.

Authors:  Kumar Saurav; Krishnan Kannabiran
Journal:  Saudi J Biol Sci       Date:  2011-08-05       Impact factor: 4.219

Review 6.  The role of soils in provision of genetic, medicinal and biochemical resources.

Authors:  Sören Thiele-Bruhn
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2021-08-04       Impact factor: 6.671

7.  Antimicrobial nisin acts against saliva derived multi-species biofilms without cytotoxicity to human oral cells.

Authors:  Jae M Shin; Islam Ateia; Jefrey R Paulus; Hongrui Liu; J Christopher Fenno; Alexander H Rickard; Yvonne L Kapila
Journal:  Front Microbiol       Date:  2015-06-18       Impact factor: 5.640

8.  Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic bacteriocin.

Authors:  Pachiyappan Kamarajan; Islam Ateia; Jae M Shin; J Christopher Fenno; Charles Le; Ling Zhan; Ana Chang; Richard Darveau; Yvonne L Kapila
Journal:  PLoS Pathog       Date:  2020-10-01       Impact factor: 6.823
  8 in total

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