Literature DB >> 12807806

Achieving evolvable Web-database bioscience applications using the EAV/CR framework: recent advances.

Luis Marenco1, Nicholas Tosches, Chiquito Crasto, Gordon Shepherd, Perry L Miller, Prakash M Nadkarni.   

Abstract

The EAV/CR framework, designed for database support of rapidly evolving scientific domains, utilizes metadata to facilitate schema maintenance and automatic generation of Web-enabled browsing interfaces to the data. EAV/CR is used in SenseLab, a neuroscience database that is part of the national Human Brain Project. This report describes various enhancements to the framework. These include (1) the ability to create "portals" that present different subsets of the schema to users with a particular research focus, (2) a generic XML-based protocol to assist data extraction and population of the database by external agents, (3) a limited form of ad hoc data query, and (4) semantic descriptors for interclass relationships and links to controlled vocabularies such as the UMLS.

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Mesh:

Year:  2003        PMID: 12807806      PMCID: PMC212781          DOI: 10.1197/jamia.M1303

Source DB:  PubMed          Journal:  J Am Med Inform Assoc        ISSN: 1067-5027            Impact factor:   4.497


  14 in total

1.  Neuronal database integration: the Senselab EAV data model.

Authors:  L Marenco; P Nadkarni; E Skoufos; G Shepherd; P Miller
Journal:  Proc AMIA Symp       Date:  1999

2.  Organization of heterogeneous scientific data using the EAV/CR representation.

Authors:  P M Nadkarni; L Marenco; R Chen; E Skoufos; G Shepherd; P Miller
Journal:  J Am Med Inform Assoc       Date:  1999 Nov-Dec       Impact factor: 4.497

3.  WebEAV: automatic metadata-driven generation of web interfaces to entity-attribute-value databases.

Authors:  P M Nadkarni; C M Brandt; L Marenco
Journal:  J Am Med Inform Assoc       Date:  2000 Jul-Aug       Impact factor: 4.497

4.  Olfactory Receptor Database: a metadata-driven automated population from sources of gene and protein sequences.

Authors:  Chiquito Crasto; Luis Marenco; Perry Miller; Gordon Shepherd
Journal:  Nucleic Acids Res       Date:  2002-01-01       Impact factor: 16.971

5.  Evaluation of an SQL model of the HELP patient database.

Authors:  S M Huff; C L Berthelsen; T A Pryor; A S Dudley
Journal:  Proc Annu Symp Comput Appl Med Care       Date:  1991

Review 6.  The Human Brain Project: neuroinformatics tools for integrating, searching and modeling multidisciplinary neuroscience data.

Authors:  G M Shepherd; J S Mirsky; M D Healy; M S Singer; E Skoufos; M S Hines; P M Nadkarni; P L Miller
Journal:  Trends Neurosci       Date:  1998-11       Impact factor: 13.837

7.  Linking a medical vocabulary to a clinical data model using Abstract Syntax Notation 1.

Authors:  S M Huff; R A Rocha; H R Solbrig; M W Barnes; S P Schrank; M Smith
Journal:  Methods Inf Med       Date:  1998-11       Impact factor: 2.176

8.  The Unified Medical Language System.

Authors:  D A Lindberg; B L Humphreys; A T McCray
Journal:  Methods Inf Med       Date:  1993-08       Impact factor: 2.176

9.  HELP the next generation: a new client-server architecture.

Authors:  S M Huff; P J Haug; L E Stevens; R C Dupont; T A Pryor
Journal:  Proc Annu Symp Comput Appl Med Care       Date:  1994

10.  Common data model for neuroscience data and data model exchange.

Authors:  D Gardner; K H Knuth; M Abato; S M Erde; T White; R DeBellis; E P Gardner
Journal:  J Am Med Inform Assoc       Date:  2001 Jan-Feb       Impact factor: 4.497

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  24 in total

1.  QIS: A framework for biomedical database federation.

Authors:  Luis Marenco; Tzuu-Yi Wang; Gordon Shepherd; Perry L Miller; Prakash Nadkarni
Journal:  J Am Med Inform Assoc       Date:  2004-08-06       Impact factor: 4.497

2.  Semi-automated population of an online database of neuronal models (ModelDB) with citation information, using PubMed for validation.

Authors:  Andrew P Davison; Thomas M Morse; Michele Migliore; Gordon M Shepherd; Michael L Hines
Journal:  Neuroinformatics       Date:  2004

3.  Guidelines for the effective use of entity-attribute-value modeling for biomedical databases.

Authors:  Valentin Dinu; Prakash Nadkarni
Journal:  Int J Med Inform       Date:  2006-11-13       Impact factor: 4.046

4.  SenseLab: new developments in disseminating neuroscience information.

Authors:  Chiquito J Crasto; Luis N Marenco; Nian Liu; Thomas M Morse; Kei-Hoi Cheung; Peter C Lai; Gautam Bahl; Peter Masiar; Hugo Y K Lam; Ernest Lim; Huajin Chen; Prakash Nadkarni; Michele Migliore; Perry L Miller; Gordon M Shepherd
Journal:  Brief Bioinform       Date:  2007-05-17       Impact factor: 11.622

5.  The Extensible Neuroimaging Archive Toolkit: an informatics platform for managing, exploring, and sharing neuroimaging data.

Authors:  Daniel S Marcus; Timothy R Olsen; Mohana Ramaratnam; Randy L Buckner
Journal:  Neuroinformatics       Date:  2007

6.  Issues in biomedical research data management and analysis: needs and barriers.

Authors:  Nicholas R Anderson; E Sally Lee; J Scott Brockenbrough; Mark E Minie; Sherrilynne Fuller; James Brinkley; Peter Tarczy-Hornoch
Journal:  J Am Med Inform Assoc       Date:  2007-04-25       Impact factor: 4.497

7.  Approaches to neuroscience data integration.

Authors:  Kei-Hoi Cheung; Ernest Lim; Matthias Samwald; Huajun Chen; Luis Marenco; Matthew E Holford; Thomas M Morse; Pradeep Mutalik; Gordon M Shepherd; Perry L Miller
Journal:  Brief Bioinform       Date:  2009-07       Impact factor: 11.622

8.  Using a community-engaged health informatics approach to develop a web analytics research platform for sharing data with community stakeholders.

Authors:  Karen H Wang; Luis Marenco; Johanna Elumn Madera; Jenerius A Aminawung; Emily A Wang; Kei-Hoi Cheung
Journal:  AMIA Annu Symp Proc       Date:  2018-04-16

9.  Semantic SenseLab: Implementing the vision of the Semantic Web in neuroscience.

Authors:  Matthias Samwald; Huajun Chen; Alan Ruttenberg; Ernest Lim; Luis Marenco; Perry Miller; Gordon Shepherd; Kei-Hoi Cheung
Journal:  Artif Intell Med       Date:  2009-12-16       Impact factor: 5.326

10.  Databases in SenseLab for the genomics, proteomics, and function of olfactory receptors.

Authors:  Luis N Marenco; Gautam Bahl; Lorra Hyland; Jing Shi; Rixin Wang; Peter C Lai; Perry L Miller; Gordon M Shepherd; Chiquito J Crasto
Journal:  Methods Mol Biol       Date:  2013
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