Literature DB >> 17460139

Issues in biomedical research data management and analysis: needs and barriers.

Nicholas R Anderson1, E Sally Lee, J Scott Brockenbrough, Mark E Minie, Sherrilynne Fuller, James Brinkley, Peter Tarczy-Hornoch.   

Abstract

OBJECTIVES: A. Identify the current state of data management needs of academic biomedical researchers. B. Explore their anticipated data management and analysis needs. C. Identify barriers to addressing those needs.
DESIGN: A multimodal needs analysis was conducted using a combination of an online survey and in-depth one-on-one semi-structured interviews. Subjects were recruited via an e-mail list representing a wide range of academic biomedical researchers in the Pacific Northwest. MEASUREMENTS: The results from 286 survey respondents were used to provide triangulation of the qualitative analysis of data gathered from 15 semi-structured in-depth interviews.
RESULTS: Three major themes were identified: 1) there continues to be widespread use of basic general-purpose applications for core data management; 2) there is broad perceived need for additional support in managing and analyzing large datasets; and 3) the barriers to acquiring currently available tools are most commonly related to financial burdens on small labs and unmet expectations of institutional support.
CONCLUSION: Themes identified in this study suggest that at least some common data management needs will best be served by improving access to basic level tools such that researchers can solve their own problems. Additionally, institutions and informaticians should focus on three components: 1) facilitate and encourage the use of modern data exchange models and standards, enabling researchers to leverage a common layer of interoperability and analysis; 2) improve the ability of researchers to maintain provenance of data and models as they evolve over time though tools and the leveraging of standards; and 3) develop and support information management service cores that could assist in these previous components while providing researchers with unique data analysis and information design support within a spectrum of informatics capabilities.

Mesh:

Year:  2007        PMID: 17460139      PMCID: PMC2244904          DOI: 10.1197/jamia.M2114

Source DB:  PubMed          Journal:  J Am Med Inform Assoc        ISSN: 1067-5027            Impact factor:   4.497


  29 in total

1.  A library-based bioinformatics services program.

Authors:  S Yarfitz; D S Ketchell
Journal:  Bull Med Libr Assoc       Date:  2000-01

2.  Requirements of a Web-based experiment management system.

Authors:  R Jakobovits; S G Soderland; R K Taira; J F Brinkley
Journal:  Proc AMIA Symp       Date:  2000

Review 3.  Toxicogenomics in risk assessment: applications and needs.

Authors:  Darrell R Boverhof; Timothy R Zacharewski
Journal:  Toxicol Sci       Date:  2005-10-12       Impact factor: 4.849

4.  Adding insight: a qualitative cross-site study of physician order entry.

Authors:  Joan S Ash; Dean F Sittig; Veena Seshadri; Richard H Dykstra; James D Carpenter; P Zoe Stavri
Journal:  Int J Med Inform       Date:  2005-08       Impact factor: 4.046

5.  A pilot bridging data integration and analytics: BioMediator and R?

Authors:  S Jeng; K Wang; J Barbero; J Brinkley; P Tarczy-Hornoch
Journal:  AMIA Annu Symp Proc       Date:  2005

Review 6.  Data integration and genomic medicine.

Authors:  Brenton Louie; Peter Mork; Fernando Martin-Sanchez; Alon Halevy; Peter Tarczy-Hornoch
Journal:  J Biomed Inform       Date:  2006-03-09       Impact factor: 6.317

7.  Customizable Electronic Laboratory Online (CELO): a web-based data management system builder for biomedical research laboratories.

Authors:  Christine Fong; James F Brinkley
Journal:  AMIA Annu Symp Proc       Date:  2006

8.  Model driven laboratory information management systems.

Authors:  Hao Li; John H Gennari; James F Brinkley
Journal:  AMIA Annu Symp Proc       Date:  2006

9.  Uncovering frustrations. A qualitative needs assessment of academic general internists as geriatric care providers and teachers.

Authors:  Craig E Tanner; Elizabeth Eckstrom; Sima S Desai; Carol L Joseph; Marnie R Ririe; Judith L Bowen
Journal:  J Gen Intern Med       Date:  2006-01       Impact factor: 5.128

Review 10.  Evaluating informatics applications--some alternative approaches: theory, social interactionism, and call for methodological pluralism.

Authors:  B Kaplan
Journal:  Int J Med Inform       Date:  2001-11       Impact factor: 4.046

View more
  40 in total

1.  MIDG-Emerging grid technologies for multi-site preclinical molecular imaging research communities.

Authors:  Jasper Lee; Jorge Documet; Brent Liu; Ryan Park; Archana Tank; H K Huang
Journal:  Int J Comput Assist Radiol Surg       Date:  2010-08-06       Impact factor: 2.924

2.  Expanding roles in a library-based bioinformatics service program: a case study.

Authors:  Meng Li; Yi-Bu Chen; William A Clintworth
Journal:  J Med Libr Assoc       Date:  2013-10

3.  Resolving complex research data management issues in biomedical laboratories: Qualitative study of an industry-academia collaboration.

Authors:  Sahiti Myneni; Vimla L Patel; G Steven Bova; Jian Wang; Christopher F Ackerman; Cynthia A Berlinicke; Steve H Chen; Mikael Lindvall; Donald J Zack
Journal:  Comput Methods Programs Biomed       Date:  2015-11-12       Impact factor: 5.428

4.  A DICOM-based 2nd generation Molecular Imaging Data Grid implementing the IHE XDS-i integration profile.

Authors:  Jasper Lee; Jianguo Zhang; Ryan Park; Grant Dagliyan; Brent Liu; H K Huang
Journal:  Int J Comput Assist Radiol Surg       Date:  2011-08-30       Impact factor: 2.924

5.  Assessment of collaboration and interoperability in an information management system to support bioscience research.

Authors:  Sahiti Myneni; Vimla L Patel
Journal:  AMIA Annu Symp Proc       Date:  2009-11-14

6.  A centralized research data repository enhances retrospective outcomes research capacity: a case report.

Authors:  Gregory William Hruby; James McKiernan; Suzanne Bakken; Chunhua Weng
Journal:  J Am Med Inform Assoc       Date:  2013-01-15       Impact factor: 4.497

Review 7.  A scoping review of qualitative research in JAMIA: past contributions and opportunities for future work.

Authors:  Mustafa I Hussain; Mayara Costa Figueiredo; Brian D Tran; Zhaoyuan Su; Stephen Molldrem; Elizabeth V Eikey; Yunan Chen
Journal:  J Am Med Inform Assoc       Date:  2021-02-15       Impact factor: 4.497

8.  Organization of Biomedical Data for Collaborative Scientific Research: A Research Information Management System.

Authors:  Sahiti Myneni; Vimla L Patel
Journal:  Int J Inf Manage       Date:  2010-06-01

9.  Application description and policy model in collaborative environment for sharing of information on epidemiological and clinical research data sets.

Authors:  Elias César Araujo de Carvalho; Adelia Portero Batilana; Julie Simkins; Henrique Martins; Jatin Shah; Dimple Rajgor; Anand Shah; Scott Rockart; Ricardo Pietrobon
Journal:  PLoS One       Date:  2010-02-19       Impact factor: 3.240

10.  SLIMS--a user-friendly sample operations and inventory management system for genotyping labs.

Authors:  Thea Van Rossum; Ben Tripp; Denise Daley
Journal:  Bioinformatics       Date:  2010-05-30       Impact factor: 6.937

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.