Literature DB >> 12458528

Mechanistic studies of HPP epoxidase: configuration of the substrate governs its enzymatic fate.

Zongbao Zhao1, Pinghua Liu, Kazuo Murakami, Tomohisa Kuzuyama, Haruo Seto, Hung-wen Liu.   

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Year:  2002        PMID： 12458528     DOI： 10.1002/1521-3773(20021202)41:23<4529::AID-ANIE4529>3.0.CO;2-2

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  26 in total

1.  Steric Enforcement of cis-Epoxide Formation in the Radical C-O-Coupling Reaction by Which (S)-2-Hydroxypropylphosphonate Epoxidase (HppE) Produces Fosfomycin.

Authors:  Shengbin Zhou; Juan Pan; Katherine M Davis; Irene Schaperdoth; Bo Wang; Amie K Boal; Carsten Krebs; J Martin Bollinger
Journal:  J Am Chem Soc       Date:  2019-12-11       Impact factor: 15.419

Review 2.  Rings, radicals, and regeneration: the early years of a bioorganic laboratory.

Authors:  Wilfred A van der Donk
Journal:  J Org Chem       Date:  2006-12-22       Impact factor: 4.354

3.  Initiating a crystallographic analysis of recombinant (S)-2-hydroxypropylphosphonic acid epoxidase from Streptomyces wedmorensis.

Authors:  Scott Cameron; Karen McLuskey; Rachel Chamberlayne; Irene Hallyburton; William N Hunter
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2005-04-28

Review 4.  Enzymatic chemistry of cyclopropane, epoxide, and aziridine biosynthesis.

Authors:  Christopher J Thibodeaux; Wei-chen Chang; Hung-wen Liu
Journal:  Chem Rev       Date:  2011-10-21       Impact factor: 60.622

Review 5.  Oxidative Cyclization in Natural Product Biosynthesis.

Authors:  Man-Cheng Tang; Yi Zou; Kenji Watanabe; Christopher T Walsh; Yi Tang
Journal:  Chem Rev       Date:  2016-12-12       Impact factor: 60.622

6.  Evidence that the fosfomycin-producing epoxidase, HppE, is a non-heme-iron peroxidase.

Authors:  Chen Wang; Wei-chen Chang; Yisong Guo; Hui Huang; Spencer C Peck; Maria E Pandelia; Geng-min Lin; Hung-wen Liu; Carsten Krebs; J Martin Bollinger
Journal:  Science       Date:  2013-10-10       Impact factor: 47.728

7.  Characterization of Two Late-Stage Enzymes Involved in Fosfomycin Biosynthesis in Pseudomonads.

Authors:  Philip Olivares; Emily C Ulrich; Jonathan R Chekan; Wilfred A van der Donk; Satish K Nair
Journal:  ACS Chem Biol       Date:  2016-12-27       Impact factor: 5.100

8.  Reaction of HppE with substrate analogues: evidence for carbon-phosphorus bond cleavage by a carbocation rearrangement.

Authors:  Wei-chen Chang; Steven O Mansoorabadi; Hung-wen Liu
Journal:  J Am Chem Soc       Date:  2013-05-23       Impact factor: 15.419

9.  Determination of the substrate binding mode to the active site iron of (S)-2-hydroxypropylphosphonic acid epoxidase using 17O-enriched substrates and substrate analogues.

Authors:  Feng Yan; Sung-Ju Moon; Pinghua Liu; Zongbao Zhao; John D Lipscomb; Aimin Liu; Hung-wen Liu
Journal:  Biochemistry       Date:  2007-10-10       Impact factor: 3.162

10.  Evidence for radical-mediated catalysis by HppE: a study using cyclopropyl and methylenecyclopropyl substrate analogues.

Authors:  Hui Huang; Wei-chen Chang; Pei-Jing Pai; Anthony Romo; Steven O Mansoorabadi; David H Russell; Hung-wen Liu
Journal:  J Am Chem Soc       Date:  2012-09-24       Impact factor: 15.419
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