Literature DB >> 11584296

A tour of structural genomics.

S E Brenner1.   

Abstract

Structural genomics projects aim to provide an experimental or computational three-dimensional model structure for all of the tractable macromolecules that are encoded by complete genomes. To this end, pilot centres worldwide are now exploring the feasibility of large-scale structure determination. Their experimental structures and computational models are expected to yield insight into the molecular function and mechanism of thousands of proteins. The pervasiveness of this information is likely to change the use of structure in molecular biology and biochemistry.

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Year:  2001        PMID： 11584296     DOI： 10.1038/35093574

Source DB:  PubMed          Journal:  Nat Rev Genet        ISSN： 1471-0056            Impact factor:   53.242


  44 in total

1.  SCOP database in 2002: refinements accommodate structural genomics.

Authors:  Loredana Lo Conte; Steven E Brenner; Tim J P Hubbard; Cyrus Chothia; Alexey G Murzin
Journal:  Nucleic Acids Res       Date:  2002-01-01       Impact factor: 16.971

2.  MAMMOTH (matching molecular models obtained from theory): an automated method for model comparison.

Authors:  Angel R Ortiz; Charlie E M Strauss; Osvaldo Olmea
Journal:  Protein Sci       Date:  2002-11       Impact factor: 6.725

3.  Multi-domain protein families and domain pairs: comparison with known structures and a random model of domain recombination.

Authors:  Gordana Apic; Wolfgang Huber; Sarah A Teichmann
Journal:  J Struct Funct Genomics       Date:  2003

4.  FoldMiner: structural motif discovery using an improved superposition algorithm.

Authors:  Jessica Shapiro; Douglas Brutlag
Journal:  Protein Sci       Date:  2004-01       Impact factor: 6.725

5.  The SWISS-MODEL Repository of annotated three-dimensional protein structure homology models.

Authors:  Jürgen Kopp; Torsten Schwede
Journal:  Nucleic Acids Res       Date:  2004-01-01       Impact factor: 16.971

6.  Accurate and automated classification of protein secondary structure with PsiCSI.

Authors:  Ling-Hong Hung; Ram Samudrala
Journal:  Protein Sci       Date:  2003-02       Impact factor: 6.725

7.  Enlarged FAMSBASE: protein 3D structure models of genome sequences for 41 species.

Authors:  Akihiro Yamaguchi; Mitsuo Iwadate; Ei-ichiro Suzuki; Kei Yura; Shigetsugu Kawakita; Hideaki Umeyama; Mitiko Go
Journal:  Nucleic Acids Res       Date:  2003-01-01       Impact factor: 16.971

8.  SWISS-MODEL: An automated protein homology-modeling server.

Authors:  Torsten Schwede; Jürgen Kopp; Nicolas Guex; Manuel C Peitsch
Journal:  Nucleic Acids Res       Date:  2003-07-01       Impact factor: 16.971

9.  Role for NMR in structural genomics.

Authors:  Michael A Kennedy; Gaetano T Montelione; Cheryl H Arrowsmith; John L Markley
Journal:  J Struct Funct Genomics       Date:  2002

10.  1H(C) and 1H(N) total NOE correlations in a single 3D NMR experiment. 15N and 13C time-sharing in t1 and t2 dimensions for simultaneous data acquisition.

Authors:  Youlin Xia; Adelinda Yee; Cheryl H Arrowsmith; Xiaolian Gao
Journal:  J Biomol NMR       Date:  2003-11       Impact factor: 2.835
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