Literature DB >> 11391306

The influence of attenuation and scatter compensation on the apparent distribution of Tc-99m sestamibi in cardiac slices.

P H Pretorius1, M V Narayanan, S T Dahlberg, J A Leppo, M A King.   

Abstract

BACKGROUND: Our objective was to study the differences in relative count distributions in the left ventricular walls with attenuation compensation (AC) versus AC and triple-energy-window scatter compensation (SC), compared with standard filtered backprojection (FBP). METHODS AND
RESULTS: Two hundred patients identified as having normal cardiac perfusion with FBP after undergoing either pharmacologically or physiologically induced stress were included in this study. Projection data were reconstructed with FBP, 10 iterations of ordered-subset expectation-maximization (OSEM) with AC, and OSEM with AC+SC. A comparison was made of average percentage of maximum counts within each of 9 regions of CEqual (Marconi Medical Systems, Inc, Cleveland, Ohio) polar maps (ie, the apex, 4 midventricular regions, and 4 basal regions). Compared with OSEM(AC), a slight decrease at the apex exists when SC is included. The elevated inferior-to-anterior count ratio in the midventricular and basal regions noted with OSEM(AC) decreased to close to 1.0 with OSEM(AC+SC). The anterior-to-lateral ratio for both regions was closest to 1.0 for OSEM(AC+SC). In the midventricular region, the lateral-to-septal ratio decreased further below 1.0 with OSEM(AC+SC) than it did with OSEM(AC). This was the only basal ratio not to improve to close to 1.0 with OSEM(AC+SC). In a subset of patients identified at the time of clinical reading as having a possible attenuation-caused decrease in the inferior region, AC elevated the inferior-to-anterior ratio to above 1.0 for the midventricular region. AC+SC resulted in a ratio of near 1.0 for this region. In another subset of patients identified as having anterior attenuation artifacts, compensation methods (either AC or AC+SC) failed to show an improvement compared with FBP.
CONCLUSIONS: AC and SC improve the uniformity of the polar map, especially by bringing the inferior-to-anterior ratio closer to 1.0. Further investigation is necessary to determine the cause of the increased midventricular septal polar map count. In addition, the subset of patients identified as having breast-like attenuation artifacts causing a decreased polar map count in the anterior wall (relative to the inferior wall) also needs further attention.

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Year:  2001        PMID: 11391306     DOI: 10.1067/mnc.2001.113516

Source DB:  PubMed          Journal:  J Nucl Cardiol        ISSN: 1071-3581            Impact factor:   5.952


  23 in total

Review 1.  Attenuation correction, or the emperor's new clothes?

Authors:  F J Wackers
Journal:  J Nucl Med       Date:  1999-08       Impact factor: 10.057

2.  Receiver operating characteristic evaluation of iterative reconstruction with attenuation correction in 99mTc-sestamibi myocardial SPECT images.

Authors:  K J LaCroix; B M Tsui; E C Frey; R J Jaszczak
Journal:  J Nucl Med       Date:  2000-03       Impact factor: 10.057

3.  Attenuation-corrected thallium-201 single-photon emission tomography using a gadolinium-153 moving line source: clinical value and the impact of attenuation correction on the extent and severity of perfusion abnormalities.

Authors:  H J Gallowitsch; J Sykora; P Mikosch; E Kresnik; O Unterweger; M Molnar; G Grimm; P Lind
Journal:  Eur J Nucl Med       Date:  1998-03

4.  Impact of attenuation correction by simultaneous emission/transmission tomography on visual assessment of 201Tl myocardial perfusion images.

Authors:  R Vidal; I Buvat; J Darcourt; O Migneco; P Desvignes; M Baudouy; F Bussière
Journal:  J Nucl Med       Date:  1999-08       Impact factor: 10.057

5.  Limited incremental diagnostic values of attenuation-noncorrected gating and ungated attenuation correction to rest/stress myocardial perfusion SPECT in patients with an intermediate likelihood of coronary artery disease.

Authors:  D S Lee; Y So; G J Cheon; K M Kim; M M Lee; J K Chung; M C Lee
Journal:  J Nucl Med       Date:  2000-05       Impact factor: 10.057

6.  Simultaneous transmission-emission thallium-201 cardiac SPECT: effect of attenuation correction on myocardial tracer distribution.

Authors:  E P Ficaro; J A Fessler; R J Ackermann; W L Rogers; J R Corbett; M Schwaiger
Journal:  J Nucl Med       Date:  1995-06       Impact factor: 10.057

Review 7.  Myocardial perfusion imaging with technetium-99m sestamibi SPECT in the evaluation of coronary artery disease.

Authors:  J Maddahi; H Kiat; K F Van Train; F Prigent; J Friedman; E V Garcia; N Alazraki; E G DePuey; K Nichols; D S Berman
Journal:  Am J Cardiol       Date:  1990-10-16       Impact factor: 2.778

8.  Evaluation of an attenuation correction method for thallium-201 myocardial perfusion tomographic imaging of patients with low likelihood of coronary artery disease.

Authors:  P Chouraqui; S Livschitz; T Sharir; N Wainer; M Wilk; I Moalem; J Baron
Journal:  J Nucl Cardiol       Date:  1998 Jul-Aug       Impact factor: 5.952

9.  Quantitative evaluation of a comprehensive motion, resolution, and attenuation correction program: initial experience.

Authors:  P Rigo; P Van Boxem; J Foulon; M Safi; J Engdahl; J Links
Journal:  J Nucl Cardiol       Date:  1998 Sep-Oct       Impact factor: 5.952

10.  A study of the liver-heart artifact in emission tomography.

Authors:  J Nuyts; P Dupont; V Van den Maegdenbergh; S Vleugels; P Suetens; L Mortelmans
Journal:  J Nucl Med       Date:  1995-01       Impact factor: 10.057

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  5 in total

1.  Clinical validation of SPECT attenuation correction using x-ray computed tomography-derived attenuation maps: multicenter clinical trial with angiographic correlation.

Authors:  Yasmin Masood; Yi-Hwa Liu; Gordon Depuey; Raymond Taillefer; Luis I Araujo; Steven Allen; Dominique Delbeke; Frank Anstett; Aharon Peretz; Mary-Jo Zito; Vera Tsatkin; Frans J Th Wackers
Journal:  J Nucl Cardiol       Date:  2005 Nov-Dec       Impact factor: 5.952

2.  Myocardial perfusion SPECT reconstruction: receiver operating characteristic comparison of CAD detection accuracy of filtered backprojection reconstruction with all of the clinical imaging information available to readers and solely stress slices iteratively reconstructed with combined compensation.

Authors:  P Hendrik Pretorius; Michael A King; Howard C Gifford; Seth T Dahlberg; Frederick Spencer; Ellen Simon; Jason Rashkin; Naomi Botkin; William Berndt; Manoj V Narayanan; Jeffrey A Leppo
Journal:  J Nucl Cardiol       Date:  2005 May-Jun       Impact factor: 5.952

3.  Scatter and attenuation correction changes interpretation of gated myocardial perfusion imaging.

Authors:  Allan Johansen; Peter Grupe; Annegrete Veje; Poul-Erik Nielsen Braad; Poul Flemming Høilund-Carlsen
Journal:  Eur J Nucl Med Mol Imaging       Date:  2004-04-29       Impact factor: 9.236

4.  Novel attenuation correction of SPECT images using scatter photopeak window data for the detection of coronary artery disease.

Authors:  Yohei Yamauchi; Yumiko Kanzaki; Kaoru Otsuka; Masuo Hayashi; Mami Okada; Shimpei Nogi; Hideaki Morita; Tsuyoshi Komori; Nobukazu Ishizaka
Journal:  J Nucl Cardiol       Date:  2013-11-02       Impact factor: 5.952

5.  Does scatter correction of cardiac SPECT improve image quality in the presence of high extracardiac activity?

Authors:  Mohammed E Khalil; Edward J Brown; Eliot N Heller
Journal:  J Nucl Cardiol       Date:  2004 Jul-Aug       Impact factor: 5.952

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