Literature DB >> 11079855

Enrolling patients into clinical trials faster using RealTime Recuiting.

A J Butte1, D A Weinstein, I S Kohane.   

Abstract

Previous work has been done on both optimizing the clinical trials process, and on sending critical laboratory results and decision support through paging systems. We report the first integration of both these solution, focusing on improving the clinical trial recruitment process. We describe a clinical trial needing a real-time method of recruiting patients in an unbiased manner, quickly enough that study tests can be obtained before patients leave or samples discarded. The report describes how the ten currently recruited patients were found and how diagnoses of potentially life-threatening disorders are being made.

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Year:  2000        PMID: 11079855      PMCID: PMC2244056     

Source DB:  PubMed          Journal:  Proc AMIA Symp        ISSN: 1531-605X


  10 in total

1.  Design of a clinical notification system.

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Journal:  Proc AMIA Symp       Date:  1999

2.  A flexible approach to guideline modeling.

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Journal:  Proc AMIA Symp       Date:  1999

3.  Notification of real-time clinical alerts generated by pharmacy expert systems.

Authors:  J E Miller; R M Reichley; L A McNamee; S A Steib; T C Bailey
Journal:  Proc AMIA Symp       Date:  1999

4.  A feasibility study of two methods for end-user configuration of a clinical event monitor.

Authors:  F C Tsui; M M Wagner; W Wilbright; A Tse; W R Hogan
Journal:  Proc AMIA Symp       Date:  1999

5.  Tool support for authoring eligibility criteria for cancer trials.

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Journal:  Proc AMIA Symp       Date:  1999

6.  Preferences of interns and residents for E-mail, paging, or traditional methods for the delivery of different types of clinical information.

Authors:  M M Wagner; S A Eisenstadt; W R Hogan; M C Pankaskie
Journal:  Proc AMIA Symp       Date:  1998

7.  A computerized laboratory alerting system.

Authors:  K E Tate; R M Gardner; L K Weaver
Journal:  MD Comput       Date:  1990 Sep-Oct

8.  Decision support for clinical trial eligibility determination in breast cancer.

Authors:  L Ohno-Machado; S J Wang; P Mar; A A Boxwala
Journal:  Proc AMIA Symp       Date:  1999

9.  Role of clinical trials informatics in the NCI's cancer informatics infrastructure.

Authors:  J Silva; R Wittes
Journal:  Proc AMIA Symp       Date:  1999

10.  Effect of computer-based alerts on the treatment and outcomes of hospitalized patients.

Authors:  D M Rind; C Safran; R S Phillips; Q Wang; D R Calkins; T L Delbanco; H L Bleich; W V Slack
Journal:  Arch Intern Med       Date:  1994-07-11
  10 in total
  30 in total

1.  Generating medical logic modules for clinical trial eligibility criteria.

Authors:  Craig G Parker; David W Embley
Journal:  AMIA Annu Symp Proc       Date:  2003

2.  The design and implementation of an open-source, data-driven cohort recruitment system: the Duke Integrated Subject Cohort and Enrollment Research Network (DISCERN).

Authors:  Jeffrey M Ferranti; William Gilbert; Jonathan McCall; Howard Shang; Tanya Barros; Monica M Horvath
Journal:  J Am Med Inform Assoc       Date:  2011-09-23       Impact factor: 4.497

3.  Efficacy and cost-effectiveness of an automated screening algorithm in an inpatient clinical trial.

Authors:  Catherine C Beauharnais; Mary E Larkin; Adrian H Zai; Emily C Boykin; Jennifer Luttrell; Deborah J Wexler
Journal:  Clin Trials       Date:  2012-02-03       Impact factor: 2.486

4.  Development of an electronic health record-based Clinical Trial Alert system to enhance recruitment at the point of care.

Authors:  Peter J Embi; Anil Jain; Jeffrey Clark; C Martin Harris
Journal:  AMIA Annu Symp Proc       Date:  2005

Review 5.  Formal representation of eligibility criteria: a literature review.

Authors:  Chunhua Weng; Samson W Tu; Ida Sim; Rachel Richesson
Journal:  J Biomed Inform       Date:  2009-12-23       Impact factor: 6.317

6.  The accuracy and efficiency of electronic screening for recruitment into a clinical trial on COPD.

Authors:  Christopher N Schmickl; Man Li; Guangxi Li; Marnie M Wetzstein; Vitaly Herasevich; Ognjen Gajic; Roberto P Benzo
Journal:  Respir Med       Date:  2011-05-14       Impact factor: 3.415

Review 7.  Biomedical informatics and outcomes research: enabling knowledge-driven health care.

Authors:  Peter J Embi; Stanley E Kaufman; Philip R O Payne
Journal:  Circulation       Date:  2009-12-08       Impact factor: 29.690

8.  Automated matching software for clinical trials eligibility: measuring efficiency and flexibility.

Authors:  Lynne Penberthy; Richard Brown; Federico Puma; Bassam Dahman
Journal:  Contemp Clin Trials       Date:  2010-03-15       Impact factor: 2.226

9.  Effect of a clinical trial alert system on physician participation in trial recruitment.

Authors:  Peter J Embi; Anil Jain; Jeffrey Clark; Susan Bizjack; Richard Hornung; C Martin Harris
Journal:  Arch Intern Med       Date:  2005-10-24

10.  A Time-and-Motion Study of Clinical Trial Eligibility Screening in a Pediatric Emergency Department.

Authors:  Judith W Dexheimer; Huaxiu Tang; Andrea Kachelmeyer; Melanie Hounchell; Stephanie Kennebeck; Imre Solti; Yizhao Ni
Journal:  Pediatr Emerg Care       Date:  2019-12       Impact factor: 1.454

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