Literature DB >> 30281551

A Time-and-Motion Study of Clinical Trial Eligibility Screening in a Pediatric Emergency Department.

Judith W Dexheimer1,2, Huaxiu Tang2,3, Andrea Kachelmeyer1, Melanie Hounchell4, Stephanie Kennebeck1, Imre Solti2, Yizhao Ni2.   

Abstract

OBJECTIVE: Challenges with efficient patient recruitment including sociotechnical barriers for clinical trials are major barriers to the timely and efficacious conduct of translational studies. We conducted a time-and-motion study to investigate the workflow of clinical trial enrollment in a pediatric emergency department.
METHODS: We observed clinical research coordinators during 3 clinically staffed shifts. One clinical research coordinator was shadowed at a time. Tasks were marked in 30-second intervals and annotated to include patient screening, patient contact, performing procedures, and physician contact. Statistical analysis was conducted on the patient enrollment activities.
RESULTS: We conducted fifteen 120-minute observations from December 12, 2013, to January 3, 2014 and shadowed 8 clinical research coordinators. Patient screening took 31.62% of their time, patient contact took 18.67%, performing procedures took 17.6%, physician contact was 1%, and other activities took 31.0%.
CONCLUSIONS: Screening patients for eligibility constituted the most time. Automated screening methods could help reduce this time. The findings suggest improvement areas in recruitment planning to increase the efficiency of clinical trial enrollment.

Entities:  

Mesh:

Year:  2019        PMID: 30281551      PMCID: PMC6445787          DOI: 10.1097/PEC.0000000000001592

Source DB:  PubMed          Journal:  Pediatr Emerg Care        ISSN: 0749-5161            Impact factor:   1.454


  32 in total

1.  Prevalence of clinically important traumatic brain injuries in children with minor blunt head trauma and isolated severe injury mechanisms.

Authors:  Lise E Nigrovic; Lois K Lee; John Hoyle; Rachel M Stanley; Marc H Gorelick; Michelle Miskin; Shireen M Atabaki; Peter S Dayan; James F Holmes; Nathan Kuppermann
Journal:  Arch Pediatr Adolesc Med       Date:  2011-12-05

2.  Efficacy and cost-effectiveness of an automated screening algorithm in an inpatient clinical trial.

Authors:  Catherine C Beauharnais; Mary E Larkin; Adrian H Zai; Emily C Boykin; Jennifer Luttrell; Deborah J Wexler
Journal:  Clin Trials       Date:  2012-02-03       Impact factor: 2.486

Review 3.  Emergency department crowding, part 1--concept, causes, and moral consequences.

Authors:  John C Moskop; David P Sklar; Joel M Geiderman; Raquel M Schears; Kelly J Bookman
Journal:  Ann Emerg Med       Date:  2008-11-22       Impact factor: 5.721

4.  Competing for patients: an ethical framework for recruiting patients with brain tumors into clinical trials.

Authors:  George M Ibrahim; Caroline Chung; Mark Bernstein
Journal:  J Neurooncol       Date:  2011-02-12       Impact factor: 4.130

5.  Emergency department conditions associated with the number of patients who leave a pediatric emergency department before physician assessment.

Authors:  Antonia Schirmer Stang; Jane McCusker; Antonio Ciampi; Erin Strumpf
Journal:  Pediatr Emerg Care       Date:  2013-10       Impact factor: 1.454

6.  Nonurgent use of the pediatric emergency department during the day.

Authors:  N M Kini; R T Strait
Journal:  Pediatr Emerg Care       Date:  1998-02       Impact factor: 1.454

7.  How do physicians and nurses spend their time in the emergency department?

Authors:  J C Hollingsworth; C D Chisholm; B K Giles; W H Cordell; D R Nelson
Journal:  Ann Emerg Med       Date:  1998-01       Impact factor: 5.721

8.  Point-of-care testing improves accuracy of STI care in an emergency department.

Authors:  Jill S Huppert; Regina G Taylor; Sarah St Cyr; Elizabeth A Hesse; Jennifer L Reed
Journal:  Sex Transm Infect       Date:  2013-03-07       Impact factor: 3.519

9.  Time motion study in a pediatric emergency department before and after computer physician order entry.

Authors:  Kenneth Yen; Elizabeth L Shane; Sachin S Pawar; Nicole D Schwendel; Robert J Zimmanck; Marc H Gorelick
Journal:  Ann Emerg Med       Date:  2008-11-20       Impact factor: 5.721

10.  Automated clinical trial eligibility prescreening: increasing the efficiency of patient identification for clinical trials in the emergency department.

Authors:  Yizhao Ni; Stephanie Kennebeck; Judith W Dexheimer; Constance M McAneney; Huaxiu Tang; Todd Lingren; Qi Li; Haijun Zhai; Imre Solti
Journal:  J Am Med Inform Assoc       Date:  2014-07-16       Impact factor: 4.497

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