Literature DB >> 10991878

Detection of the high-level aminoglycoside resistance gene aph(2")-Ib in Enterococcus faecium.

S J Kao1, I You, D B Clewell, S M Donabedian, M J Zervos, J Petrin, K J Shaw, J W Chow.   

Abstract

A new high-level gentamicin resistance gene, designated aph(2")-Ib, was cloned from Enterococcus faecium SF11770. The deduced amino acid sequence of the 897-bp open reading frame of aph(2")-Ib shares homology with the aminoglycoside-modifying enzymes AAC(6')-APH(2"), APH(2")-Ic, and APH(2")-Id. The observed phosphotransferase activity is designated APH(2")-Ib.

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Year:  2000        PMID： 10991878      PMCID： PMC90169          DOI： 10.1128/AAC.44.10.2876-2879.2000

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  17 in total

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Journal:  J Clin Microbiol       Date:  1989-04       Impact factor: 5.948

3.  In vitro susceptibility and molecular analysis of gentamicin-resistant enterococci.

Authors:  J W Chow; S M Donabedian; D B Clewell; D F Sahm; M J Zervos
Journal:  Diagn Microbiol Infect Dis       Date:  1998-11       Impact factor: 2.803

4.  Nucleotide sequence analysis of the gene specifying the bifunctional 6'-aminoglycoside acetyltransferase 2"-aminoglycoside phosphotransferase enzyme in Streptococcus faecalis and identification and cloning of gene regions specifying the two activities.

Authors:  J J Ferretti; K S Gilmore; P Courvalin
Journal:  J Bacteriol       Date:  1986-08       Impact factor: 3.490

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Authors:  I You; R Kariyama; M J Zervos; H Kumon; J W Chow
Journal:  Diagn Microbiol Infect Dis       Date:  2000-01       Impact factor: 2.803

6.  The aacA-aphD gentamicin and kanamycin resistance determinant of Tn4001 from Staphylococcus aureus: expression and nucleotide sequence analysis.

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Journal:  J Gen Microbiol       Date:  1987-11

7.  A comprehensive set of sequence analysis programs for the VAX.

Authors:  J Devereux; P Haeberli; O Smithies
Journal:  Nucleic Acids Res       Date:  1984-01-11       Impact factor: 16.971

8.  Highly efficient protoplast transformation system for Streptococcus faecalis and a new Escherichia coli-S. faecalis shuttle vector.

Authors:  R Wirth; F Y An; D B Clewell
Journal:  J Bacteriol       Date:  1986-03       Impact factor: 3.490

9.  High-level resistance to gentamicin in clinical isolates of Streptococcus (Enterococcus) faecium.

Authors:  G M Eliopoulos; C Wennersten; S Zighelboim-Daum; E Reiszner; D Goldmann; R C Moellering
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  36 in total

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Journal:  Antimicrob Agents Chemother       Date:  2003-04       Impact factor: 5.191

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Journal:  Antimicrob Agents Chemother       Date:  2002-10       Impact factor: 5.191

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10.  High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm.

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