Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Three-dimensional Poisson-Nernst-Planck theory studies: influence of membrane electrostatics on gramicidin A channel conductance.

Literature DB >> 10866939

Three-dimensional Poisson-Nernst-Planck theory studies: influence of membrane electrostatics on gramicidin A channel conductance.

A E Cárdenas¹, R D Coalson, M G Kurnikova.

Abstract

A recently introduced real-space lattice methodology for solving the three-dimensional Poisson-Nernst-Planck equations is used to compute current-voltage relations for ion permeation through the gramicidin A ion channel embedded in membranes characterized by surface dipoles and/or surface charge. Comparisons to a variety of experimental results, presented herein, have proven largely successful. Strengths and weaknesses of the method are discussed.

Mesh：

Substances：

Year: 2000 PMID： 10866939 PMCID： PMC1300917 DOI： 10.1016/S0006-3495(00)76275-8

Source DB: PubMed Journal: Biophys J ISSN： 0006-3495 Impact factor: 4.033

36 in total

1. Permeation of ions across the potassium channel: Brownian dynamics studies.

Authors: S H Chung; T W Allen; M Hoyles; S Kuyucak
Journal: Biophys J Date: 1999-11 Impact factor: 4.033

2. A lattice relaxation algorithm for three-dimensional Poisson-Nernst-Planck theory with application to ion transport through the gramicidin A channel.

Authors: M G Kurnikova; R D Coalson; P Graf; A Nitzan
Journal: Biophys J Date: 1999-02 Impact factor: 4.033

3. Exploration of the structural features defining the conduction properties of a synthetic ion channel.

Authors: G R Dieckmann; J D Lear; Q Zhong; M L Klein; W F DeGrado; K A Sharp
Journal: Biophys J Date: 1999-02 Impact factor: 4.033

4. Surface charge, surface dipoles and membrane conductance.

Authors: D A Haydon; V B Myers
Journal: Biochim Biophys Acta Date: 1973-05-25

5. Theoretical analysis of hydrophobic matching and membrane-mediated interactions in lipid bilayers containing gramicidin.

Authors: T A Harroun; W T Heller; T M Weiss; L Yang; H W Huang
Journal: Biophys J Date: 1999-06 Impact factor: 4.033

Review 6. Modeling of ion channels.

Authors: D G Levitt
Journal: J Gen Physiol Date: 1999-06 Impact factor: 4.086

7. Surface charge and the conductance of phospholipid membranes.

Authors: S G McLaughlin; G Szabo; G Eisenman; S M Ciani
Journal: Proc Natl Acad Sci U S A Date: 1970-11 Impact factor: 11.205

Review 8. Progress and prospects in permeation.

Authors: W Nonner; D P Chen; B Eisenberg
Journal: J Gen Physiol Date: 1999-06 Impact factor: 4.086

Review 9. Ionic hopping defended.

Authors: C Miller
Journal: J Gen Physiol Date: 1999-06 Impact factor: 4.086

10. Test of Poisson-Nernst-Planck theory in ion channels.

Authors: B Corry; S Kuyucak; S H Chung
Journal: J Gen Physiol Date: 1999-10 Impact factor: 4.086

42 in total

1. The formation and dynamics of proton wires in channel environments.

Authors: M L Brewer; U W Schmitt; G A Voth
Journal: Biophys J Date: 2001-04 Impact factor: 4.033

2. Model channel ion currents in NaCl-extended simple point charge water solution with applied-field molecular dynamics.

Authors: P S Crozier; D Henderson; R L Rowley; D D Busath
Journal: Biophys J Date: 2001-12 Impact factor: 4.033

3. Why can't protons move through water channels?

Authors: Bob Eisenberg
Journal: Biophys J Date: 2003-12 Impact factor: 4.033

4. The role of the dielectric barrier in narrow biological channels: a novel composite approach to modeling single-channel currents.

Authors: Artem B Mamonov; Rob D Coalson; Abraham Nitzan; Maria G Kurnikova
Journal: Biophys J Date: 2003-06 Impact factor: 4.033

10. Energy variational analysis of ions in water and channels: Field theory for primitive models of complex ionic fluids.

Authors: Bob Eisenberg; Yunkyong Hyon; Chun Liu
Journal: J Chem Phys Date: 2010-09-14 Impact factor: 3.488