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Literature DB >> 10836264

Polyphosphorylation and non-enzymatic template-directed ligation of oligonucleotides.

Abstract

Oligonucleotide 5'-polyphosphates are formed under potentially prebiotic conditions from oligonucleotide 5'-phosphates and sodium trimetaphosphate. Oligonucleotides activated as polyphosphates undergo template-directed ligation. We believe that these reactions could have produced longer oligonucleotide products from shorter substrates under prebiotic conditions.

Entities: Chemical

Keywords: NASA Discipline Exobiology; Non-NASA Center

Mesh：

Substances：

Year: 2000 PMID： 10836264 DOI： 10.1023/a:1006683507864

Source DB: PubMed Journal: Orig Life Evol Biosph ISSN： 0169-6149 Impact factor: 1.950

13 in total

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6 in total

1. Phosphorylation of adenosine with trimetaphosphate under simulated prebiotic conditions.

Authors: Changmei Cheng; Chang Fan; Rong Wan; Chunyuan Tong; Zhiwei Miao; Jing Chen; Yufen Zhao
Journal: Orig Life Evol Biosph Date: 2002-06 Impact factor: 1.950

2. Generation of long RNA chains in water.

Authors: Giovanna Costanzo; Samanta Pino; Fabiana Ciciriello; Ernesto Di Mauro
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Authors: Michael L Manapat; Irene A Chen; Martin A Nowak
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Authors: Albert D G de Roos
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5. Prebiotic formation of cyclic dipeptides under potentially early Earth conditions.

Authors: Jianxi Ying; Rongcan Lin; Pengxiang Xu; Yile Wu; Yan Liu; Yufen Zhao
Journal: Sci Rep Date: 2018-01-17 Impact factor: 4.379

6. Prebiotically Plausible RNA Activation Compatible with Ribozyme-Catalyzed Ligation.

Authors: Emilie Yeonwha Song; Eddy Ivanhoe Jiménez; Huacan Lin; Kristian Le Vay; Ramanarayanan Krishnamurthy; Hannes Mutschler
Journal: Angew Chem Int Ed Engl Date: 2020-12-10 Impact factor: 16.823

6 in total