Literature DB >> 1058491

Distribution of allelic frequencies in a finite population under stepwise production of neutral alleles.

M Kimura, T Ohta.   

Abstract

A formula for the distribution of allelic frequencies in a finite population is derived assuming stepwise production of multiple alleles. Monte Carlo experiments were performed to check the validity of the formula, and excellent agreement was obtained between theoretical distribution and experimental results. The formula should be useful for analyzing genetic variability in natural populations that can be detected by electrophoretic methods.

Mesh:

Year:  1975        PMID: 1058491      PMCID: PMC432851          DOI: 10.1073/pnas.72.7.2761

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  11 in total

1.  THE NUMBER OF ALLELES THAT CAN BE MAINTAINED IN A FINITE POPULATION.

Authors:  M KIMURA; J F CROW
Journal:  Genetics       Date:  1964-04       Impact factor: 4.562

2.  The Distribution of Gene Frequencies Under Irreversible Mutation.

Authors:  S Wright
Journal:  Proc Natl Acad Sci U S A       Date:  1938-07       Impact factor: 11.205

Review 3.  Mutational pressure as the main cause of molecular evolution and polymorphism.

Authors:  T Ota
Journal:  Nature       Date:  1974-11-29       Impact factor: 49.962

4.  Simulation studies on electrophoretically detectable genetic variability in a finite population.

Authors:  T Ohta; M Kimura
Journal:  Genetics       Date:  1974-03       Impact factor: 4.562

5.  Isoallele frequencies in very large populations.

Authors:  J L King
Journal:  Genetics       Date:  1974-03       Impact factor: 4.562

6.  Mutation and evolution at the molecular level.

Authors:  M Kimura; T Ohta
Journal:  Genetics       Date:  1973-04       Impact factor: 4.562

7.  The probability of electrophoretic idendity of proteins as a function of amino acid divergence.

Authors:  J L King
Journal:  J Mol Evol       Date:  1973-11-27       Impact factor: 2.395

8.  Genetic distance and electrophoretic identity of proteins between taxa.

Authors:  M Nei; R Chakraborty
Journal:  J Mol Evol       Date:  1973-11-27       Impact factor: 2.395

9.  A model of mutation appropriate to estimate the number of electrophoretically detectable alleles in a finite population.

Authors:  T Ohta; M Kimura
Journal:  Genet Res       Date:  1973-10       Impact factor: 1.588

10.  Genetic variability maintained in a finite population due to mutational production of neutral and nearly neutral isoalleles.

Authors:  M Kimura
Journal:  Genet Res       Date:  1968-06       Impact factor: 1.588

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  35 in total

1.  Allele excess at neutrally evolving microsatellites and the implications for tests of neutrality.

Authors:  Christian Schlötterer; Max Kauer; Daniel Dieringer
Journal:  Proc Biol Sci       Date:  2004-04-22       Impact factor: 5.349

2.  Electrophoretically silent alleles in a finite population.

Authors:  M Nei; R Chakraborty
Journal:  J Mol Evol       Date:  1976-12-30       Impact factor: 2.395

3.  The number of alleles at a microsatellite defines the allele frequency spectrum and facilitates fast accurate estimation of theta.

Authors:  Ryan J Haasl; Bret A Payseur
Journal:  Mol Biol Evol       Date:  2010-07-06       Impact factor: 16.240

4.  Microsatellite polymorphism in natural populations of the wild plant Arabidopsis thaliana.

Authors:  H Innan; R Terauchi; N T Miyashita
Journal:  Genetics       Date:  1997-08       Impact factor: 4.562

5.  Infinite allele model with varying mutation rate.

Authors:  M Nei; R Chakraborty; P A Fuerst
Journal:  Proc Natl Acad Sci U S A       Date:  1976-11       Impact factor: 11.205

6.  Sex-chromosome differentiation and 'sex races' in the common frog (Rana temporaria).

Authors:  Nicolas Rodrigues; Yvan Vuille; Jon Loman; Nicolas Perrin
Journal:  Proc Biol Sci       Date:  2015-05-07       Impact factor: 5.349

7.  Maintenance of Genetic Variability under the Joint Effect of Mutation, Selection and Random Drift.

Authors:  W H Li
Journal:  Genetics       Date:  1978-10       Impact factor: 4.562

8.  Statistical Studies on Protein Polymorphism in Natural Populations. III. Distribution of Allele Frequencies and the Number of Alleles per Locus.

Authors:  R Chakraborty; P A Fuerst; M Nei
Journal:  Genetics       Date:  1980-04       Impact factor: 4.562

9.  A Mixed Model of Mutation for Electrophoretic Identity of Proteins within and between Populations.

Authors:  W H Li
Journal:  Genetics       Date:  1976-06       Impact factor: 4.562

10.  Genetic diversity of four populations of Qualea grandiflora Mart. in fragments of the Brazilian Cerrado.

Authors:  Lia Maris Orth Ritter Antiqueira; Paulo Yoshio Kageyama
Journal:  Genetica       Date:  2013-12-19       Impact factor: 1.082

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