Literature DB >> 1011266

Electrophoretically silent alleles in a finite population.

M Nei, R Chakraborty.   

Abstract

The expected number of silent alleles in an electromorph is computed for various values of population size (N), mutation rate (u), and sample size (s) under the assumption of no selection. The proportion of alleles undetectable by electrophoresis is higher when Nu is large than when this is small. It is shown that an electromorph of high population frequency has more silent alleles than an electromorph of low frequency if the sample size is the same.

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Year:  1976        PMID: 1011266     DOI: 10.1007/bf01739262

Source DB:  PubMed          Journal:  J Mol Evol        ISSN: 0022-2844            Impact factor:   2.395


  13 in total

1.  The charge-state model of protein polymorphism in natural populations.

Authors:  D R Marshall; A H Brown
Journal:  J Mol Evol       Date:  1975-11-04       Impact factor: 2.395

2.  THE NUMBER OF ALLELES THAT CAN BE MAINTAINED IN A FINITE POPULATION.

Authors:  M KIMURA; J F CROW
Journal:  Genetics       Date:  1964-04       Impact factor: 4.562

3.  Distribution of allelic frequencies in a finite population under stepwise production of neutral alleles.

Authors:  M Kimura; T Ohta
Journal:  Proc Natl Acad Sci U S A       Date:  1975-07       Impact factor: 11.205

4.  The structures of cytochrome c and the rates of molecular evolution.

Authors:  R E Dickerson
Journal:  J Mol Evol       Date:  1971       Impact factor: 2.395

5.  Simulation studies on electrophoretically detectable genetic variability in a finite population.

Authors:  T Ohta; M Kimura
Journal:  Genetics       Date:  1974-03       Impact factor: 4.562

6.  Genetic distance and electrophoretic identity of proteins between taxa.

Authors:  M Nei; R Chakraborty
Journal:  J Mol Evol       Date:  1973-11-27       Impact factor: 2.395

7.  The sampling theory of selectively neutral alleles.

Authors:  W J Ewens
Journal:  Theor Popul Biol       Date:  1972-03       Impact factor: 1.570

8.  A model of mutation appropriate to estimate the number of electrophoretically detectable alleles in a finite population.

Authors:  T Ohta; M Kimura
Journal:  Genet Res       Date:  1973-10       Impact factor: 1.588

Review 9.  Electrophoretic variation in enzymes.

Authors:  C R Shaw
Journal:  Science       Date:  1965-08-27       Impact factor: 47.728

10.  Extraordinary incidence of electrophoretically silent genetic polymorphisms.

Authors:  S H Boyer
Journal:  Nature       Date:  1972-10-20       Impact factor: 49.962

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  6 in total

1.  Simulation results with stepwise mutation model and their interpretations.

Authors:  R Chakraborty
Journal:  J Mol Evol       Date:  1977-08-05       Impact factor: 2.395

2.  Genic heterogeneity within electrophoretic "alleles" and the pattern of variation among loci in Drosophila pseudoobscura.

Authors:  R S Singh
Journal:  Genetics       Date:  1979-12       Impact factor: 4.562

3.  Frequency of private electrophoretic variants and indirect estimates of mutation rate in Papua New Guinea.

Authors:  K K Bhatia; N M Blake; S W Serjeantson; R L Kirk
Journal:  Am J Hum Genet       Date:  1981-01       Impact factor: 11.025

4.  Population genetic characteristics of the D1S80 locus in seven human populations.

Authors:  R Deka; S DeCroo; L Jin; S T McGarvey; F Rothhammer; R E Ferrell; R Chakraborty
Journal:  Hum Genet       Date:  1994-09       Impact factor: 4.132

5.  Composite stepwise mutation model under the neutral mutation hypothesis.

Authors:  N Takahata
Journal:  J Mol Evol       Date:  1980-03       Impact factor: 2.395

6.  Estimating total genic diversity in the house mouse.

Authors:  F Bonhomme; R K Selander
Journal:  Biochem Genet       Date:  1978-04       Impact factor: 1.890

  6 in total

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