| Literature DB >> 10422839 |
C N Pace1, G R Grimsley, S T Thomas, G I Makhatadze.
Abstract
The change in heat capacity deltaCp for the folding of ribonuclease A was determined using differential scanning calorimetry and thermal denaturation curves. The methods gave equivalent results, deltaCp = 1.15+/-0.08 kcal mol(-1) K(-1). Estimates of the conformational stability of ribonuclease A based on these results from thermal unfolding are in good agreement with estimates from urea unfolding analyzed using the linear extrapolation method.Entities:
Mesh:
Substances:
Year: 1999 PMID: 10422839 PMCID: PMC2144378 DOI: 10.1110/ps.8.7.1500
Source DB: PubMed Journal: Protein Sci ISSN: 0961-8368 Impact factor: 6.725