| Literature DB >> 10220391 |
R I Dima1, J R Banavar, M Cieplak, A Maritan.
Abstract
A strategy is outlined for obtaining the free energy of a typical designed heteropolymer. The design procedure considers the probability that the target conformation is occupied in comparison with all the other conformations that could house the given sequence. Numerical calculations on lattice heteropolymer models are presented to illustrate the key physical principles.Mesh:
Substances:
Year: 1999 PMID: 10220391 PMCID: PMC21789 DOI: 10.1073/pnas.96.9.4904
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205