Literature DB >> 9868373

The origin of life--a review of facts and speculations.

L E Orgel1.   

Abstract

Three popular hypotheses attempt to explain the origin of prebiotic molecules: synthesis in a reducing atmosphere, input in meteorites and synthesis on metal sulfides in deep-sea vents. It is not possible to decide which is correct. It is also unclear whether the RNA world was the first biological world or whether some simpler world preceded it.

Entities:  

Keywords:  NASA Discipline Exobiology; Non-NASA Center

Mesh:

Substances:

Year:  1998        PMID: 9868373     DOI: 10.1016/s0968-0004(98)01300-0

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN: 0968-0004            Impact factor:   13.807


  57 in total

1.  Evolutionarily conserved binding of ribosomes to the translocation channel via the large ribosomal RNA.

Authors:  A Prinz; C Behrens; T A Rapoport; E Hartmann; K U Kalies
Journal:  EMBO J       Date:  2000-04-17       Impact factor: 11.598

2.  A system of two polymerases--a model for the origin of life.

Authors:  V Kunin
Journal:  Orig Life Evol Biosph       Date:  2000-10       Impact factor: 1.950

Review 3.  Gene duplication and other evolutionary strategies: from the RNA world to the future.

Authors:  Jürgen Brosius
Journal:  J Struct Funct Genomics       Date:  2003

Review 4.  A case for the extreme antiquity of recombination.

Authors:  Niles Lehman
Journal:  J Mol Evol       Date:  2003-06       Impact factor: 2.395

5.  Combinatorial minimization and secondary structure determination of a nucleotide synthase ribozyme.

Authors:  Kelly E Chapple; David P Bartel; Peter J Unrau
Journal:  RNA       Date:  2003-10       Impact factor: 4.942

Review 6.  Noisy clues to the origin of life.

Authors:  David C Krakauer; Akira Sasaki
Journal:  Proc Biol Sci       Date:  2002-12-07       Impact factor: 5.349

7.  Causation and the origin of life. Metabolism or replication first?

Authors:  Addy Pross
Journal:  Orig Life Evol Biosph       Date:  2004-06       Impact factor: 1.950

8.  An overlooked riddle of life's origins: energy-dependent nucleic acid unzipping.

Authors:  Ladislav Kovác; Jozef Nosek; L'ubomír Tomáska
Journal:  J Mol Evol       Date:  2003       Impact factor: 2.395

Review 9.  Closing the circle: replicating RNA with RNA.

Authors:  Leslie K L Cheng; Peter J Unrau
Journal:  Cold Spring Harb Perspect Biol       Date:  2010-06-16       Impact factor: 10.005

10.  Montmorillonite, oligonucleotides, RNA and origin of life.

Authors:  Gözen Ertem
Journal:  Orig Life Evol Biosph       Date:  2004-12       Impact factor: 1.950

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