| Literature DB >> 9735012 |
Abstract
A new general role for redundant (apparently non-coding) DNA is speculated: buffering the effect of fluctuations in intra-cellular solute composition on chromatin condensation state in its condensed form and on binding of DNA-tropic proteins and other ligands in its decondensed form. The "buffering" DNA performing such passive-homeostasis (energy-independent) function, can provide selective advantage in ecological niches with a low energy supply.Mesh:
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Year: 1998 PMID: 9735012 DOI: 10.1006/jtbi.1997.0629
Source DB: PubMed Journal: J Theor Biol ISSN: 0022-5193 Impact factor: 2.691