Literature DB >> 9730504

Symptomatic and clinical improvement in morbidly obese patients with gastroesophageal reflux disease following Roux-en-Y gastric bypass.

S C Smith1, C B Edwards, G N Goodman.   

Abstract

BACKGROUND: Patients who suffer with gastroesophageal reflux Disease (GERD) endure a worsening of symptoms as their weight increases. When medical treatment of this condition in the morbidly obese patients fails, surgical intervention may be indicated. Choosing a procedure which not only helps achieve weight control but which also relieves symptoms and complications of GERD is the goal. We present a review of patients who have undergone Roux-en-Y Gastric Bypass (RYGBP) and related procedures for this disease.
METHODS: One hundred eighty-eight patients undergoing surgery for morbid obesity and for GERD in 1992-1996 were contacted by mail or phone. All of these patients had undergone preoperative esophagogastroduodenoscopy to grade the severity of their disease. Their preoperative symptoms were compared to those experienced postoperatively.
RESULTS: One hundred thirty patients underwent a RYGBP with modified Hill fundopexy, 22 patients underwent a distal gastrectomy with modified Hill fundopexy, 8 patients underwent distal gastrectomy alone and 28 patients underwent RYGBP alone. There have been no deaths. There were nine surgical complications, eight early and one at 2.5 years postoperation. Follow-up is 4-48 months. The average BMI dropped from 43 to 30.2 kg/m2. Whereas all patients were on some form of medical therapy before surgery, only 14 reported the need for medication postoperatively.
CONCLUSIONS: Surgical intervention for weight control and treatment of GERD has been highly successful in our experience both with respect to weight control and to the reduction of reflux symptoms. Depending upon endoscopic and operative findings a RYGBP with or without an antireflux procedure can provide dramatic improvement. Gastrectomy with antireflux modifications is appropriate in selected cases.

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Mesh:

Year:  1997        PMID: 9730504     DOI: 10.1381/096089297765555205

Source DB:  PubMed          Journal:  Obes Surg        ISSN: 0960-8923            Impact factor:   4.129


  30 in total

1.  Barrett's esophagus before and after Roux-en-Y gastric bypass for severe obesity.

Authors:  Brandon Andrew; Joshua B Alley; Cristina E Aguilar; Robert D Fanelli
Journal:  Surg Endosc       Date:  2017-08-04       Impact factor: 4.584

Review 2.  Guidelines for surgical treatment of gastroesophageal reflux disease.

Authors:  Dimitrios Stefanidis; William W Hope; Geoffrey P Kohn; Patrick R Reardon; William S Richardson; Robert D Fanelli
Journal:  Surg Endosc       Date:  2010-08-20       Impact factor: 4.584

3.  Obesity and antireflux surgery.

Authors:  K B Jones
Journal:  Surg Endosc       Date:  2002-09       Impact factor: 4.584

4.  Roux-en-Y reconstruction for failed fundoplication.

Authors:  Konstantinos I Makris; Tommy Lee; Sumeet K Mittal
Journal:  J Gastrointest Surg       Date:  2009-09-02       Impact factor: 3.452

Review 5.  Obesity and GERD.

Authors:  Paul Chang; Frank Friedenberg
Journal:  Gastroenterol Clin North Am       Date:  2013-12-27       Impact factor: 3.806

6.  Patterns of reoperation after failed fundoplication: an analysis of 9462 patients.

Authors:  Nabeel R Obeid; Maria S Altieri; Jie Yang; Jihye Park; Kristie Price; Andrew Bates; Aurora D Pryor
Journal:  Surg Endosc       Date:  2017-07-13       Impact factor: 4.584

7.  Surgical management of gastroesophageal reflux disease in obesity.

Authors:  Sayeed Ikramuddin
Journal:  Dig Dis Sci       Date:  2008-07-29       Impact factor: 3.199

8.  Laparoscopic anti-reflux surgery is effective in obese patients with gastro-oesophageal reflux disease.

Authors:  Vivien V Ng; Michael I Booth; Jane J Stratford; Linda Jones; J Sohanpal; Thomas C B Dehn
Journal:  Ann R Coll Surg Engl       Date:  2007-10       Impact factor: 1.891

9.  Histological esophagitis before and after surgical treatment of morbid obesity (Capella technique): a prospective study.

Authors:  Galzuinda Maria Figueiredo Reis; Paulo Roberto Savassi-Rocha; Ana Margarida M F Nogueira; Marcílio José Rodrigues Lima; Silas de Carvalho; Vitor Arantes; Carlos Alberto Barros; Omar Lopes Cançado
Journal:  Obes Surg       Date:  2008-02-22       Impact factor: 4.129

10.  Effects of bariatric surgery in older patients.

Authors:  Harvey J Sugerman; Eric J DeMaria; John M Kellum; Elizabeth L Sugerman; Jill G Meador; Luke G Wolfe
Journal:  Ann Surg       Date:  2004-08       Impact factor: 12.969

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