Literature DB >> 17959008

Laparoscopic anti-reflux surgery is effective in obese patients with gastro-oesophageal reflux disease.

Vivien V Ng1, Michael I Booth, Jane J Stratford, Linda Jones, J Sohanpal, Thomas C B Dehn.   

Abstract

INTRODUCTION: Obesity has long been regarded as a risk factor for the development of gastro-oesophageal reflux disease (GORD). It has been claimed that surgical efficacy of laparoscopic anti-reflux operations is decreased in obese patients. The aim of this study was to assess whether laparoscopic anti-reflux surgery is effective in obese patients with GORD compared to non-obese patients. PATIENTS AND METHODS: A total of 366 patients (mean age 44 years; range, 12-86 years) underwent laparoscopic anti-reflux surgery between 1997-2003. Of these, 74 patients were considered obese; 58 patients had a body mass index (BMI) of 30-34 kg/m(2) and 16 were classified as morbidly obese with a BMI >or= 35 kg/m(2). Pre-operative symptomatic scoring, indications for surgery, pH studies, operative times and complications were compared between obese and non-obese patients. Symptomatic outcome and Visick score between the two groups were assessed at 6 weeks, 6 months and 1 year following surgery.
RESULTS: Failure of medical treatment was the main reason for surgery in all groups. Operative time was longer in obese patients (mean time 93 min compared to 81 min; P = 0.0007), the main difficulty being gaining access because of their body habitus. All groups found the procedure to be effective in symptomatic outcome, 91% of obese patients compared to 92% of non-obese patients scored Visick I or II at 6 weeks' postoperatively. Similar Visick scoring was shown between the two groups at 6 months and 1 year, and in the morbidly obese group.
CONCLUSIONS: The outcome of laparoscopic anti-reflux surgery is similar between obese and non-obese patients with no trend towards a worse outcome in the obese or morbidly obese. Obesity should not be seen as a contra-indication, although it may be more technically challenging in this group of patients. Good results can be achieved in obese patients.

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Year:  2007        PMID: 17959008      PMCID: PMC2121261          DOI: 10.1308/003588407X205323

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  19 in total

1.  Obesity adversely affects the outcome of antireflux operations.

Authors:  A R Perez; A C Moncure; D W Rattner
Journal:  Surg Endosc       Date:  2001-06-12       Impact factor: 4.584

2.  When fundoplication fails: redo?

Authors:  C Daniel Smith; David A McClusky; Murad Abu Rajad; Andrew B Lederman; John G Hunter
Journal:  Ann Surg       Date:  2005-06       Impact factor: 12.969

3.  Symptomatic improvement in gastroesophageal reflux disease (GERD) following laparoscopic Roux-en-Y gastric bypass.

Authors:  E E Frezza; S Ikramuddin; W Gourash; T Rakitt; A Kingston; J Luketich; P Schauer
Journal:  Surg Endosc       Date:  2002-05-03       Impact factor: 4.584

4.  Obesity and its effect on outcome of laparoscopic Nissen fundoplication.

Authors:  J Fraser; D I Watson; C J O'Boyle; G G Jamieson
Journal:  Dis Esophagus       Date:  2001       Impact factor: 3.429

5.  Results of laparoscopic Nissen fundoplication at 2-8 years after surgery.

Authors:  M I Booth; L Jones; J Stratford; T C B Dehn
Journal:  Br J Surg       Date:  2002-04       Impact factor: 6.939

6.  Risk factors for complications of laparoscopic Nissen fundoplication.

Authors:  D Hahnloser; M Schumacher; R Cavin; B Cosendey; P Petropoulos
Journal:  Surg Endosc       Date:  2001-10-13       Impact factor: 4.584

7.  Obesity does not adversely affect the outcome of laparoscopic antireflux surgery (LARS).

Authors:  E R Winslow; M M Frisella; N J Soper; M E Klingensmith
Journal:  Surg Endosc       Date:  2003-10-28       Impact factor: 4.584

8.  Comparison of objective outcomes following laparoscopic Nissen fundoplication versus laparoscopic gastric bypass in the morbidly obese with heartburn.

Authors:  E J Patterson; D G Davis; Y Khajanchee; L L Swanström
Journal:  Surg Endosc       Date:  2003-07-21       Impact factor: 4.584

Review 9.  The role of the hiatus hernia in gastro-oesophageal reflux disease.

Authors:  C Gordon; J Y Kang; P J Neild; J D Maxwell
Journal:  Aliment Pharmacol Ther       Date:  2004-10-01       Impact factor: 8.171

Review 10.  Gastro-oesophageal reflux disease in obesity: pathophysiological and therapeutic considerations.

Authors:  N Barak; E D Ehrenpreis; J R Harrison; M D Sitrin
Journal:  Obes Rev       Date:  2002-02       Impact factor: 9.213

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  9 in total

Review 1.  Guidelines for surgical treatment of gastroesophageal reflux disease.

Authors:  Dimitrios Stefanidis; William W Hope; Geoffrey P Kohn; Patrick R Reardon; William S Richardson; Robert D Fanelli
Journal:  Surg Endosc       Date:  2010-08-20       Impact factor: 4.584

2.  The combined effect of age and body mass index on outcomes in foregut surgery: a regression model analysis of the National Surgical Quality Improvement Program data.

Authors:  Prashanth Palvannan; Irving Miranda; Aziz M Merchant
Journal:  Surg Endosc       Date:  2015-09-16       Impact factor: 4.584

3.  Is laparoscopic antireflux surgery safe and effective in obese patients?

Authors:  Koray Tekin; Toygar Toydemir; Mehmet Ali Yerdel
Journal:  Surg Endosc       Date:  2011-08-24       Impact factor: 4.584

4.  Obesity does not affect the outcome of laparoscopic antireflux surgery.

Authors:  Ruzica-Rosalia Luketina; Oliver Owen Koch; Gernot Köhler; Stavros A Antoniou; Klaus Emmanuel; Rudolph Pointner
Journal:  Surg Endosc       Date:  2014-10-08       Impact factor: 4.584

5.  The role of body mass index in determining clinical and quality of life outcomes after laparoscopic anti-reflux surgery.

Authors:  Zachary Sanford; Shyam Jayaraman; Adam S Weltz; H Reza Zahiri; Adrian Park
Journal:  Surg Endosc       Date:  2019-05-06       Impact factor: 4.584

Review 6.  ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease.

Authors:  Philip O Katz; Kerry B Dunbar; Felice H Schnoll-Sussman; Katarina B Greer; Rena Yadlapati; Stuart Jon Spechler
Journal:  Am J Gastroenterol       Date:  2022-01-01       Impact factor: 10.864

Review 7.  Safety and effectiveness of antireflux surgery in obese patients.

Authors:  A Tandon; R Rao; A Hotouras; Q M Nunes; M Hartley; R Gunasekera; N Howes
Journal:  Ann R Coll Surg Engl       Date:  2017-09       Impact factor: 1.891

8.  Short- and Long-Term, 11-22 Years, Results after Laparoscopic Nissen Fundoplication in Obese versus Nonobese Patients.

Authors:  Mario Schietroma; Federica Piccione; Marco Clementi; Emanuela Marina Cecilia; Federico Sista; Beatrice Pessia; Francesco Carlei; Stefano Guadagni; Gianfranco Amicucci
Journal:  J Obes       Date:  2017-05-11

Review 9.  Pre-operative clinical and instrumental factors as antireflux surgery outcome predictors.

Authors:  Salvatore Tolone; Giorgia Gualtieri; Edoardo Savarino; Marzio Frazzoni; Nicola de Bortoli; Manuele Furnari; Giuseppina Casalino; Simona Parisi; Vincenzo Savarino; Ludovico Docimo
Journal:  World J Gastrointest Surg       Date:  2016-11-27
  9 in total

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