Literature DB >> 18293045

Histological esophagitis before and after surgical treatment of morbid obesity (Capella technique): a prospective study.

Galzuinda Maria Figueiredo Reis1, Paulo Roberto Savassi-Rocha, Ana Margarida M F Nogueira, Marcílio José Rodrigues Lima, Silas de Carvalho, Vitor Arantes, Carlos Alberto Barros, Omar Lopes Cançado.   

Abstract

BACKGROUND: The effects of vertical banded gastroplasty/Roux-en-Y gastric bypass (Capella) on the esophageal mucosa of patients with histological esophagitis are poorly understood. To evaluate long-term effects, we investigated the persistence, aggravation or disappearance of histological esophagitis in patients with morbid obesity and reflux esophagitis (diagnosed by endoscopic biopsy) after Roux-en-Y gastric bypass.
METHODS: Twenty-one patients with morbid obesity and esophagitis (histological diagnosis) were submitted to gastric bypass (Fobi-Capella technique) and underwent upper endoscopy and esophageal biopsy during the late postoperative period.
RESULTS: The mean age of the patients was 42.57 +/- 7.49 years (30 to 56). Nineteen (90.48%) patients were women, and two (9.52%) were men. Before surgery, the patients presented a mean weight of 124.26 +/- 19.09 kg and a mean body mass index (BMI) of 48.46 +/- 6.37 kg/m(2). Thirteen (61.90%) patients had endoscopic esophagitis before surgery. The mean weight and BMI were 81.65 +/- 13.16 kg and 31.91 +/- 4.99 kg/m(2), respectively, during the late postoperative period (29.80 +/- 8.91 months). The mean percentage of excess weight loss was 68.7 +/- 14.6%. Among the 21 patients with a preoperative histological diagnosis of reflux esophagitis, five (23.18%) had the same diagnosis after surgery, and four (19.04%) continued to present findings of endoscopic esophagitis.
CONCLUSION: Vertical banded gastroplasty/Roux-en-Y gastric bypass (Capella technique) is effective in the treatment of reflux esophagitis. No association was observed between the percentage of excess weight loss and improvement of esophagitis.

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Year:  2008        PMID: 18293045     DOI: 10.1007/s11695-008-9447-5

Source DB:  PubMed          Journal:  Obes Surg        ISSN: 0960-8923            Impact factor:   4.129


  26 in total

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Journal:  World J Surg       Date:  1998-09       Impact factor: 3.352

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Journal:  Obes Surg       Date:  1994-11       Impact factor: 4.129

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Journal:  Gastroenterology       Date:  1970-02       Impact factor: 22.682

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Journal:  Dig Dis Sci       Date:  1999-11       Impact factor: 3.199

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Authors:  Jon Charles Gould; Michael Joseph Garren; James Ralph Starling
Journal:  J Gastrointest Surg       Date:  2004-12       Impact factor: 3.452

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Journal:  Surg Clin North Am       Date:  2001-10       Impact factor: 2.741

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Journal:  Am J Surg       Date:  1995-03       Impact factor: 2.565

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Journal:  Dig Dis Sci       Date:  1991-10       Impact factor: 3.199

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  2 in total

1.  Laparoscopic silastic ring mini-gastric bypass: a single centre experience.

Authors:  M G Clarke; K Wong; L Pearless; M Booth
Journal:  Obes Surg       Date:  2013-11       Impact factor: 4.129

2.  Clinical Endoscopic and Histologic Findings of a Long-Term Follow-Up (10.7 Years) After Roux-en-Y Laparoscopic Gastric Bypass: a Prospective Study.

Authors:  Attila J Csendes; Deycies L Gaete; Bárbara M Carreño; Benjamín Panza
Journal:  Obes Surg       Date:  2022-07-01       Impact factor: 3.479

  2 in total

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