| Literature DB >> 24503366 |
Paul Chang1, Frank Friedenberg2.
Abstract
Epidemiologic data have demonstrated that obesity is an important risk factor for the development of gastroesophageal reflux disease (GERD). There is also accumulating data that obesity is associated with complications related to longstanding reflux such as erosive esophagitis, Barrett esophagus, and esophageal adenocarcinoma. Central obesity, rather than body mass index, appears to be more closely associated with these complications. Surgical data are confounded by the concomitant repair of prevalent hiatal hernias in many patients.Entities:
Keywords: Adiponectin; Barrett esophagus; Gastroesophageal reflux disease; Leptin; Obesity; Waist-to-hip ratio
Mesh:
Year: 2013 PMID: 24503366 PMCID: PMC3920303 DOI: 10.1016/j.gtc.2013.11.009
Source DB: PubMed Journal: Gastroenterol Clin North Am ISSN: 0889-8553 Impact factor: 3.806