Literature DB >> 9687417

Inhibition of human immunodeficiency virus type 1 infection in SCID-hu Thy/Liv mice by the G-quartet-forming oligonucleotide, ISIS 5320.

C A Stoddart1, L Rabin, M Hincenbergs, M Moreno, V Linquist-Stepps, J M Leeds, L A Truong, J R Wyatt, D J Ecker, J M McCune.   

Abstract

Viral replication was inhibited in a dose-dependent manner after administration of the phosphorothioate oligonucleotide TTGGGGTT (ISIS 5320) to human immunodeficiency virus type 1 (HIV-1)-infected SCID-hu Thy/Liv mice. Potent in vivo antiviral activity was observed against the T-cell-tropic molecular clone NL4-3; the agent was found to have weak activity against one primary HIV-1 isolate, and the agent was inactive against a second primary isolate.

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Year:  1998        PMID： 9687417      PMCID： PMC105876     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  9 in total

1.  Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays.

Authors:  T Mosmann
Journal:  J Immunol Methods       Date:  1983-12-16       Impact factor: 2.303

2.  HIV induces thymus depletion in vivo.

Authors:  M L Bonyhadi; L Rabin; S Salimi; D A Brown; J Kosek; J M McCune; H Kaneshima
Journal:  Nature       Date:  1993-06-24       Impact factor: 49.962

3.  Antiviral efficacy in vivo of the anti-human immunodeficiency virus bicyclam SDZ SID 791 (JM 3100), an inhibitor of infectious cell entry.

Authors:  R Datema; L Rabin; M Hincenbergs; M B Moreno; S Warren; V Linquist; B Rosenwirth; J Seifert; J M McCune
Journal:  Antimicrob Agents Chemother       Date:  1996-03       Impact factor: 5.191

4.  Use of standardized SCID-hu Thy/Liv mouse model for preclinical efficacy testing of anti-human immunodeficiency virus type 1 compounds.

Authors:  L Rabin; M Hincenbergs; M B Moreno; S Warren; V Linquist; R Datema; B Charpiot; J Seifert; H Kaneshima; J M McCune
Journal:  Antimicrob Agents Chemother       Date:  1996-03       Impact factor: 5.191

5.  HIV-1-induced thymocyte depletion is associated with indirect cytopathogenicity and infection of progenitor cells in vivo.

Authors:  L Su; H Kaneshima; M Bonyhadi; S Salimi; D Kraft; L Rabin; J M McCune
Journal:  Immunity       Date:  1995-01       Impact factor: 31.745

6.  Potent and specific inhibition of HIV envelope-mediated cell fusion and virus binding by G quartet-forming oligonucleotide (ISIS 5320).

Authors:  R W Buckheit; J L Roberson; C Lackman-Smith; J R Wyatt; T A Vickers; D J Ecker
Journal:  AIDS Res Hum Retroviruses       Date:  1994-11       Impact factor: 2.205

7.  Combinatorially selected guanosine-quartet structure is a potent inhibitor of human immunodeficiency virus envelope-mediated cell fusion.

Authors:  J R Wyatt; T A Vickers; J L Roberson; R W Buckheit; T Klimkait; E DeBaets; P W Davis; B Rayner; J L Imbach; D J Ecker
Journal:  Proc Natl Acad Sci U S A       Date:  1994-02-15       Impact factor: 11.205

8.  The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function.

Authors:  J M McCune; R Namikawa; H Kaneshima; L D Shultz; M Lieberman; I L Weissman
Journal:  Science       Date:  1988-09-23       Impact factor: 47.728

9.  Long-term human hematopoiesis in the SCID-hu mouse.

Authors:  R Namikawa; K N Weilbaecher; H Kaneshima; E J Yee; J M McCune
Journal:  J Exp Med       Date:  1990-10-01       Impact factor: 14.307
  9 in total
  10 in total

1.  Antiviral activity of 2'-deoxy-3'-oxa-4'-thiocytidine (BCH-10652) against lamivudine-resistant human immunodeficiency virus type 1 in SCID-hu Thy/Liv mice.

Authors:  C A Stoddart; M E Moreno; V D Linquist-Stepps; C Bare; M R Bogan; A Gobbi; R W Buckheit; J Bedard; R F Rando; J M McCune
Journal:  Antimicrob Agents Chemother       Date:  2000-03       Impact factor: 5.191

2.  CpG oligodeoxynucleotides block human immunodeficiency virus type 1 replication in human lymphoid tissue infected ex vivo.

Authors:  Erika Schlaepfer; Annette Audigé; Barbara von Beust; Vania Manolova; Markus Weber; Helene Joller; Martin F Bachmann; Thomas M Kundig; Roberto F Speck
Journal:  J Virol       Date:  2004-11       Impact factor: 5.103

3.  Inhibition of human immunodeficiency virus type 1 activity in vitro by a new self-stabilized oligonucleotide with guanosine-thymidine quadruplex motifs.

Authors:  Jun-ichiro Suzuki; Naoko Miyano-Kurosaki; Tomoyuki Kuwasaki; Hiroaki Takeuchi; Gota Kawai; Hiroshi Takaku
Journal:  J Virol       Date:  2002-03       Impact factor: 5.103

Review 4.  The transgenic rabbit as model for human diseases and as a source of biologically active recombinant proteins.

Authors:  Zs Bosze; L Hiripi; J W Carnwath; H Niemann
Journal:  Transgenic Res       Date:  2003-10       Impact factor: 2.788

5.  Experimental transmission of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) to SCID-hu Thy/Liv mice.

Authors:  D Dittmer; C Stoddart; R Renne; V Linquist-Stepps; M E Moreno; C Bare; J M McCune; D Ganem
Journal:  J Exp Med       Date:  1999-12-20       Impact factor: 14.307

Review 6.  G-quadruplexes in viruses: function and potential therapeutic applications.

Authors:  Mathieu Métifiot; Samir Amrane; Simon Litvak; Marie-Line Andreola
Journal:  Nucleic Acids Res       Date:  2014-10-20       Impact factor: 16.971

7.  Monomolecular G-quadruplex structures with inversion of polarity sites: new topologies and potentiality.

Authors:  Antonella Virgilio; Annapina Russo; Teresa Amato; Giulia Russo; Luciano Mayol; Veronica Esposito; Aldo Galeone
Journal:  Nucleic Acids Res       Date:  2017-08-21       Impact factor: 16.971

Review 8.  G-quadruplex-based aptamers against protein targets in therapy and diagnostics.

Authors:  Chiara Platella; Claudia Riccardi; Daniela Montesarchio; Giovanni N Roviello; Domenica Musumeci
Journal:  Biochim Biophys Acta Gen Subj       Date:  2016-11-16       Impact factor: 3.770

9.  Validation of the SCID-hu Thy/Liv mouse model with four classes of licensed antiretrovirals.

Authors:  Cheryl A Stoddart; Cheryl A Bales; Jennifer C Bare; George Chkhenkeli; Sofiya A Galkina; April N Kinkade; Mary E Moreno; José M Rivera; Rollie E Ronquillo; Barbara Sloan; Paul L Black
Journal:  PLoS One       Date:  2007-08-01       Impact factor: 3.240

10.  Identification of G-quadruplex forming sequences in three manatee papillomaviruses.

Authors:  Maryam Zahin; William L Dean; Shin-Je Ghim; Joongho Joh; Robert D Gray; Sujita Khanal; Gregory D Bossart; Antonio A Mignucci-Giannoni; Eric C Rouchka; Alfred B Jenson; John O Trent; Jonathan B Chaires; Julia H Chariker
Journal:  PLoS One       Date:  2018-04-09       Impact factor: 3.240
  10 in total

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